Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using MBS766795 (ARHGEF5 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer (pH9) .)
Rabbit ARHGEF5 Polyclonal Antibody | anti-ARHGEF5 antibody
ARHGEF5 Rabbit Polyclonal
Immunogen Affinity Purified
Immunogen Affinity Purified
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using MBS766795 (ARHGEF5 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer (pH9) .)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using MBS766795 (ARHGEF5 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer (pH9) .)
Testing Data
()
Testing Data
()
Western Blot (WB)
(MCF7 cells were subjected to SDS PAGE followed by western blot with MBS766795 (ARHGEF5 antibody) at dilution of 1:500)
Western Blot (WB)
(MCF7 cells were subjected to SDS PAGE followed by western blot with MBS766795 (ARHGEF5 antibody) at dilution of 1:500)
NCBI and Uniprot Product Information
NCBI Description
Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization. [provided by RefSeq, Jul 2008]
Uniprot Description
ARHGEF5: 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; GEFs; GEFs, Rac/Rho; Oncoprotein
Chromosomal Location of Human Ortholog: 7q35
Cellular Component: cell junction; cell projection; cytoplasm; nucleoplasm; nucleus; plasma membrane; podosome
Molecular Function: GTP binding; guanyl-nucleotide exchange factor activity; lipid binding; protein binding; Rho guanyl-nucleotide exchange factor activity
Biological Process: actin cytoskeleton organization and biogenesis; myeloid dendritic cell chemotaxis; positive regulation of GTPase activity; positive regulation of JNK activity; positive regulation of stress fiber formation; positive regulation of transcription factor activity; regulation of actin cytoskeleton organization and biogenesis; regulation of cytoskeleton organization and biogenesis; regulation of GTPase activity; regulation of Rho protein signal transduction
Research Articles on ARHGEF5
Similar Products
Product Notes
The ARHGEF5 arhgef5 (Catalog #AAA766795) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ARHGEF5 Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ARHGEF5 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the ARHGEF5 arhgef5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ARHGEF5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
