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Immunohistochemistry (IHC) (Anti-ARHGAP18 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.)

Rabbit ARHGAP18 Polyclonal Antibody | anti-ARHGAP18 antibody

Rabbit Polyclonal to Human ARHGAP18

Gene Names
ARHGAP18; SENEX; MacGAP; bA307O14.2
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Immunocytochemistry, Western Blot, ELISA
Purity
Immunoaffinity Purified
Synonyms
ARHGAP18; Polyclonal Antibody; Rabbit Polyclonal to Human ARHGAP18; Anti-ARHGAP18 Antibody (C-Terminus) IHC-plus; BA307O14.2; MacGAP; SENEX; Human ARHGAP18; anti-ARHGAP18 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
Human ARHGAP18
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.02% sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
171115067
Applicable Applications for anti-ARHGAP18 antibody
Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Western Blot (WB), ELISA (EIA)
Application Notes
ELISA, ICC, IHC-P (2.5 - 5 ug/ml), WB (1 - 2 ug/ml)
Usage: ARHGAP18 antibody can be used for detection of ARHGAP18 by Western blot at 1-2 ug/ml.
Target Species
Human
Immunogen Description
A 15 amino acid peptide near the carboxy terminus of human ARHGAP18.
Immunogen Type
Synthetic peptide
Immunogen
ARHGAP18 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human ARHGAP18.
Antigen Modification
C-Terminus
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.

Immunohistochemistry (IHC)

(Anti-ARHGAP18 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.)

Immunohistochemistry (IHC) (Anti-ARHGAP18 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.)

Immunohistochemistry (IHC)

(Anti-ARHGAP18 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.)

Immunohistochemistry (IHC) (Anti-ARHGAP18 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.)

Immunofluorescence (IF)

(Immunofluorescence of ARHGAP18 in 3T3 cells with ARHGAP18 antibody at 20 ug/ml.)

Immunofluorescence (IF) (Immunofluorescence of ARHGAP18 in 3T3 cells with ARHGAP18 antibody at 20 ug/ml.)

Immunocytochemistry (ICC)

(Immunocytochemistry of ARHGAP18 in 3T3 cells with ARHGAP18 antibody at 2.5 ug/ml.)

Immunocytochemistry (ICC) (Immunocytochemistry of ARHGAP18 in 3T3 cells with ARHGAP18 antibody at 2.5 ug/ml.)

Western Blot (WB)

(Western blot analysis of ARHGAP18 in 3T3 cell lysate with ARHGAP18 antibody at (A) 1 and (B) 2 ug/ml.)

Western Blot (WB) (Western blot analysis of ARHGAP18 in 3T3 cell lysate with ARHGAP18 antibody at (A) 1 and (B) 2 ug/ml.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
70,164 Da
NCBI Official Full Name
Homo sapiens chromosome 6, GRCh37.p13 Primary Assembly
NCBI Official Synonym Full Names
Rho GTPase activating protein 18
NCBI Official Symbol
ARHGAP18
NCBI Official Synonym Symbols
SENEX; MacGAP; bA307O14.2
NCBI Protein Information
rho GTPase-activating protein 18; ARHGAP18; rho-type GTPase-activating protein 18
UniProt Protein Name
Rho GTPase-activating protein 18
UniProt Gene Name
ARHGAP18
UniProt Entry Name
RHG18_HUMAN

NCBI Description

ARHGAP18 belongs to a family of Rho (see MIM 165390) GTPase-activating proteins that modulate cell signaling (Potkin et al., 2009 [PubMed 19065146]).[supplied by OMIM, Apr 2010]

Uniprot Description

ARHGAP18: a GTPase activator for the Rho-type GTPases, converting them to inactive GDP-bound states. Two alternatively-spliced isoforms have been described.

Protein type: GAPs; GAPs, Rac/Rho

Chromosomal Location of Human Ortholog: 6q22.33

Cellular Component: cytosol

Molecular Function: GTPase activator activity

Biological Process: regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; positive regulation of GTPase activity

Research Articles on ARHGAP18

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Product Notes

The ARHGAP18 arhgap18 (Catalog #AAA247543) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human ARHGAP18 reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ARHGAP18 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Western Blot (WB), ELISA (EIA). ELISA, ICC, IHC-P (2.5 - 5 ug/ml), WB (1 - 2 ug/ml) Usage: ARHGAP18 antibody can be used for detection of ARHGAP18 by Western blot at 1-2 ug/ml. Researchers should empirically determine the suitability of the ARHGAP18 arhgap18 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ARHGAP18, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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