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Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using MBS7128422(ARAP1 Antibody) at dilution 1/80, on the right is treated with synthetic peptide. (Original magnification: ×200))

Rabbit anti-Human, Mouse ARAP1 Polyclonal Antibody | anti-ARAP1 antibody

ARAP1 Antibody

Gene Names
ARAP1; CENTD2
Reactivity
Human, Mouse
Applications
ELISA, Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
ARAP1; Polyclonal Antibody; ARAP1 Antibody; ArfGAP with RhoGAP domain; ankyrin repeat and PH domain 1; anti-ARAP1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
Liquid; In Phosphate Buffered Saline, pH 7.4, 0.05% NaN3, and 40% Glycerol
Applicable Applications for anti-ARAP1 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:2000-1:10000
IHC: 1:100-1:300
Immunogen
Synthetic peptide of human ARAP1
Immunogen Species
Human
Conjugate
Non-conjugated
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using MBS7128422(ARAP1 Antibody) at dilution 1/80, on the right is treated with synthetic peptide. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using MBS7128422(ARAP1 Antibody) at dilution 1/80, on the right is treated with synthetic peptide. (Original magnification: ×200))
Product Categories/Family for anti-ARAP1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
136,264 Da
NCBI Official Full Name
centaurin, delta 2, isoform CRA_d
NCBI Official Synonym Full Names
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
NCBI Official Symbol
ARAP1
NCBI Official Synonym Symbols
CENTD2
NCBI Protein Information
arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1
UniProt Protein Name
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1
UniProt Gene Name
ARAP1
UniProt Synonym Gene Names
CENTD2; KIAA0782; Cnt-d2

NCBI Description

The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]

Uniprot Description

Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Has a preference for ARF1 and ARF5 ().

Research Articles on ARAP1

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Product Notes

The ARAP1 arap1 (Catalog #AAA7128422) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ARAP1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ARAP1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). ELISA: 1:2000-1:10000 IHC: 1:100-1:300. Researchers should empirically determine the suitability of the ARAP1 arap1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ARAP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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