Rabbit anti-Human Aquaporin 6 Polyclonal Antibody | anti-Aqp6 antibody
Aquaporin 6 (WCH3, hKID, AQP2-like)
Gene Names
Aqp6; AI790337
Reactivity
Human
Applications
ELISA, Western Blot, Immunofluorescence
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
Aquaporin 6; Polyclonal Antibody; Aquaporin 6 (WCH3; hKID; AQP2-like); Anti -Aquaporin 6 (WCH3; anti-Aqp6 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human Aquaporin 6.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a lyophilized powder from PBS, 0.1% BSA, 0.05% sodium azide. Reconstitute with 100ul sterile PBS.
Applicable Applications for anti-Aqp6 antibody
ELISA (EL/EIA), Western Blot (WB), Immunofluorescence (IF)
Application Notes
Suitable for use in ELISA, Western Blot. and Immunofluorescence Other appications not tested.
Dilution: ELISA: 0.5-1ug.mlusing control peptide to coat plates to 1ug/ml.
Western Blot: 1-10ug/ml (ECL)
Immunofluorescence: 2-10ug/ml in paraformaldehyde fixed sections
Dilution: ELISA: 0.5-1ug.mlusing control peptide to coat plates to 1ug/ml.
Western Blot: 1-10ug/ml (ECL)
Immunofluorescence: 2-10ug/ml in paraformaldehyde fixed sections
Immunogen
A synthetic peptide corresponding to 19aa near the C-terminal, cytoplamic domain of human Aquaporin 6.
Species Sequence Homology
Rat, 47%
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-Aqp6 antibody
Water is a critical component of all living cells. Interestingly, tissue membranes show a great degree of water permeability. Mammalian red cells, renal proximal tubules, and descending thin limb of Henle are extraordinarily permeable to water. Water crosses hydrophobic plasma membranes either by simple diffusion or through a facilitative transport mechanism mediated by special protein "aquaporin". Over the last decade, genes for several members of aquaporin family have been cloned, expressed, and their distribution studied in many tissues. AQP6 (WCH3 or hKID or AQP2-like; 282 aa; 29 kDa; chromosome 12q13; rat 276 aa) is found only in the kidney with low water permeability. Human AQP6 is alternatively spliced to isoform 2, a 163 aa protein that contains 2 extra internal regions, which leads to translations shift and an early termination, as compared to the 282- aa isoform 1. the isoform 2 contains an identical N-terminal 134-aa and a distinct 29-aa C-terminus. Human AQP6 AQP families of proteins are predicted to contain six transmembrane domains. The N and C-terminus are predicted to be cytoplasmic. AQP6 shows greatest homology with hMIP (48%) and hAQP-2 (52%). It also has similarity with human MIWC (AQP4; 34%), CHIP-28 (AQP1; 38%), and GLIP (AQP3; 22%).
Product Categories/Family for anti-Aqp6 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
28,849 Da
NCBI Official Full Name
aquaporin 6
NCBI Official Synonym Full Names
aquaporin 6
NCBI Official Symbol
Aqp6
NCBI Official Synonym Symbols
AI790337
NCBI Protein Information
aquaporin-6; AQP-6
UniProt Protein Name
Aqp6 protein
Protein Family
UniProt Gene Name
Aqp6
UniProt Synonym Gene Names
AQP6
UniProt Entry Name
Q14BV5_MOUSE
Uniprot Description
AQP6: Forms a water-specific channel that participates in distinct physiological functions such as glomerular filtration, tubular endocytosis and acid-base metabolism. Belongs to the MIP/aquaporin (TC 1.A.8) family.
Protein type: Transporter, aquaporin family; Membrane protein, multi-pass; Transporter; Membrane protein, integral
Cellular Component: membrane; integral to plasma membrane; apical plasma membrane; integral to membrane; cytoplasmic vesicle
Molecular Function: anion channel activity; nitrate transmembrane transporter activity; transporter activity; water channel activity; glycerol channel activity
Biological Process: glycerol transport; cellular water homeostasis; transport; water transport; cellular response to stress; transmembrane transport; nitrate transport
Research Articles on Aqp6
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Product Notes
The Aqp6 aqp6 (Catalog #AAA625467) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Aquaporin 6 (WCH3, hKID, AQP2-like) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Aquaporin 6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunofluorescence (IF). Suitable for use in ELISA, Western Blot. and Immunofluorescence Other appications not tested. Dilution: ELISA: 0.5-1ug.mlusing control peptide to coat plates to 1ug/ml. Western Blot: 1-10ug/ml (ECL) Immunofluorescence: 2-10ug/ml in paraformaldehyde fixed sections. Researchers should empirically determine the suitability of the Aqp6 aqp6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Aquaporin 6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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