Western Blot (WB)
Rabbit Aquaporin 2 Polyclonal Antibody | anti-AQP2 antibody
Aquaporin 2 Antibody
Immunoprecipitation: 1:200
Western Blot: 1:500
Western Blot (WB)
Western Blot (WB)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a water channel protein located in the kidney collecting tubule. It belongs to the MIP/aquaporin family, some members of which are clustered together on chromosome 12q13. Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus. [provided by RefSeq, Oct 2008]
Uniprot Description
AQP2: Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Expressed in renal collecting tubules. Belongs to the MIP/aquaporin (TC 1.A.8) family.
Protein type: Membrane protein, multi-pass; Channel, misc.; Transporter, aquaporin family; Transporter; Membrane protein, integral
Cellular Component: apical plasma membrane; basolateral plasma membrane; clathrin-coated vesicle; cytoplasm; cytoplasmic vesicle; cytoplasmic vesicle membrane; early endosome; integral to plasma membrane; lysosome; membrane; plasma membrane; pore complex; protein complex; recycling endosome; rough endoplasmic reticulum; trans-Golgi network; transport vesicle
Molecular Function: actin binding; glycerol channel activity; glycerol transmembrane transporter activity; PDZ domain binding; porin activity; protein binding; water channel activity; water transporter activity
Biological Process: actin filament depolymerization; aging; apoptosis; cell volume homeostasis; cellular response to water deprivation; cellular water homeostasis; female pregnancy; glycerol transport; hyperosmotic response; positive regulation of calcium ion transport; renal water transport; response to calcium ion; response to glucagon stimulus; response to hormone stimulus; response to lipopolysaccharide; response to lithium ion; response to salt stress; response to starvation; response to water deprivation; transmembrane transport; water homeostasis; water transport
Research Articles on AQP2
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Product Notes
The AQP2 aqp2 (Catalog #AAA540219) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Aquaporin 2 Antibody reacts with Bovine, Human, Mouse, Rat, Sheep and may cross-react with other species as described in the data sheet. AAA Biotech's Aquaporin 2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB). ELISA: 1:10,000 Immunoprecipitation: 1:200 Western Blot: 1:500. Researchers should empirically determine the suitability of the AQP2 aqp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Aquaporin 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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