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Western Blot (WB) (AQP1 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the AQP1 antibody detected the AQP1 protein (arrow).)

Rabbit AQP1 Polyclonal Antibody | anti-AQP1 antibody

AQP1 Antibody (C-term)

Gene Names
AQP1; CO; CHIP28; AQP-CHIP
Reactivity
Human, mouse (Predicted Reactivity: Bovine, Rat)
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
AQP1; Polyclonal Antibody; AQP1 Antibody (C-term); Aquaporin-1; AQP-1; Aquaporin-CHIP; Urine water channel; Water channel protein for red blood cells and kidney proximal tubule; CHIP28; anti-AQP1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, mouse (Predicted Reactivity: Bovine, Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This AQP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241-269 amino acids from the C-terminal region of human AQP1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
241-269
Sequence Length
154
Applicable Applications for anti-AQP1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(AQP1 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the AQP1 antibody detected the AQP1 protein (arrow).)

Western Blot (WB) (AQP1 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the AQP1 antibody detected the AQP1 protein (arrow).)

Western Blot (WB)

(AQP1 Antibody (C-term) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the AQP1 antibody detected the AQP1 protein (arrow).)

Western Blot (WB) (AQP1 Antibody (C-term) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the AQP1 antibody detected the AQP1 protein (arrow).)
Related Product Information for anti-AQP1 antibody
Aquaporins are a family of small integral membrane
proteins related to the major intrinsic protein (MIP or AQP0). This
gene encodes an aquaporin which functions as a molecular water
channel protein. It is a homotetramer with 6 bilayer spanning
domains and N-glycosylation sites. The protein physically resembles
channel proteins and is abundant in erythrocytes and renal tubes.
The gene encoding this aquaporin is a possible candidate for
disorders involving imbalance in ocular fluid movement. Several
transcript variants encoding different isoforms have been found for
this gene.
Product Categories/Family for anti-AQP1 antibody
References
Chen, L.M., et al. Am. J. Physiol. Regul. Integr. Comp. Physiol. 299 (5), R1163-R1174 (2010) :
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Shankardas, J., et al. Mol. Vis. 16, 1538-1548 (2010) :
Halverson, G.R., et al. Immunohematology 26(1):22-26(2010)
Sui, H., et al. Nature 414(6866):872-878(2001)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
358
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
28526
NCBI Official Full Name
aquaporin-1 isoform 2
NCBI Official Synonym Full Names
aquaporin 1 (Colton blood group)
NCBI Official Symbol
AQP1
NCBI Official Synonym Symbols
CO; CHIP28; AQP-CHIP
NCBI Protein Information
aquaporin-1
UniProt Protein Name
Aquaporin-1
UniProt Gene Name
AQP1
UniProt Synonym Gene Names
CHIP28; AQP-1
UniProt Entry Name
AQP1_HUMAN

NCBI Description

Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This gene encodes an aquaporin which functions as a molecular water channel protein. It is a homotetramer with 6 bilayer spanning domains and N-glycosylation sites. The protein physically resembles channel proteins and is abundant in erythrocytes and renal tubes. The gene encoding this aquaporin is a possible candidate for disorders involving imbalance in ocular fluid movement. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]

Uniprot Description

AQP1: Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Belongs to the MIP/aquaporin (TC 1.A.8) family.

Protein type: Transporter; Membrane protein, integral; Transporter, aquaporin family; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 7p14

Cellular Component: nuclear membrane; integral to plasma membrane; basolateral plasma membrane; brush border membrane; apical part of cell; cytoplasm; apical plasma membrane; plasma membrane; basal plasma membrane; nerve terminal; nucleus; sarcolemma; brush border

Molecular Function: protein binding; potassium channel activity; ephrin receptor binding; water transporter activity; intracellular cGMP activated cation channel activity; ammonium transmembrane transporter activity; glycerol transmembrane transporter activity; potassium ion transmembrane transporter activity; water channel activity; nitric oxide transporter activity; transmembrane transporter activity; glycerol channel activity

Biological Process: glycerol transport; cGMP biosynthetic process; cerebrospinal fluid secretion; wound healing; cellular response to stress; water transport; carbon dioxide transport; negative regulation of caspase activity; sensory perception of pain; pancreatic juice secretion; positive regulation of saliva secretion; odontogenesis; positive regulation of fibroblast proliferation; hyperosmotic salinity response; nitric oxide transport; bicarbonate transport; multicellular organismal water homeostasis; cellular homeostasis; transmembrane transport; lateral ventricle development; potassium ion transport; lipid digestion; response to drug; cellular water homeostasis; secretory granule organization and biogenesis; glomerular filtration; ammonium transport; positive regulation of angiogenesis; renal water transport; camera-type eye morphogenesis; adrenocorticotropin hormone secretion; response to estrogen stimulus; establishment and/or maintenance of actin cytoskeleton polarity; renal water homeostasis; cell volume homeostasis; negative regulation of apoptosis

Disease: Blood Group--colton

Research Articles on AQP1

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Product Notes

The AQP1 aqp1 (Catalog #AAA9201314) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 241-269. The AQP1 Antibody (C-term) reacts with Human, mouse (Predicted Reactivity: Bovine, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's AQP1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the AQP1 aqp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AQP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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