Rabbit anti-Human Apolipoprotein A2 (APOA2) Polyclonal Antibody | anti-APOA2 antibody
APC-Linked Polyclonal Antibody to Apolipoprotein A2 (APOA2)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a component of high density lipoproteins (HDL). Mice lacking the encoded protein have low HDL-cholesterol levels, smaller HDL particles, increased clearance of triglyceride-rich lipoproteins and insulin hypersensitivity. Transgenic mice overexpressing the encoded protein have elevated levels of HDL-cholesterol and show increased susceptibility to atherosclerosis. Alternative splicing of this gene results in multiple variants. [provided by RefSeq, Mar 2015]
Uniprot Description
APOA2: May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism. Belongs to the apolipoprotein A2 family.
Protein type: Endoplasmic reticulum; Lipid-binding; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 1 H3|1 79.22 cM
Cellular Component: chylomicron; extracellular space
Molecular Function: apolipoprotein receptor binding; cholesterol binding; cholesterol transporter activity; high-density lipoprotein binding; lipase inhibitor activity; lipid binding; lipid transporter activity; phosphatidylcholine binding; phospholipid binding; protein heterodimerization activity; protein homodimerization activity
Biological Process: cholesterol efflux; cholesterol homeostasis; cholesterol metabolic process; cholesterol transport; diacylglycerol catabolic process; lipid transport; lipoprotein metabolic process; negative regulation of cholesterol transport; negative regulation of cytokine secretion during immune response; negative regulation of lipase activity; negative regulation of lipid catabolic process; organ regeneration; peptidyl-methionine modification; phosphatidylcholine biosynthetic process; phospholipid catabolic process; phospholipid efflux; positive regulation of interleukin-8 biosynthetic process; positive regulation of lipid catabolic process; protein amino acid oxidation; regulation of cholesterol absorption; regulation of protein stability; response to glucose stimulus; reverse cholesterol transport
Research Articles on APOA2
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Product Notes
The APOA2 apoa2 (Catalog #AAA2044853) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The APC-Linked Polyclonal Antibody to Apolipoprotein A2 (APOA2) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Apolipoprotein A2 (APOA2) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA). Researchers should empirically determine the suitability of the APOA2 apoa2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Apolipoprotein A2 (APOA2), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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