Western Blot (WB)
(Western Blot analysis of APOBEC3C expression in transfected 293T cell line by APOBEC3C polyclonal antibody. Lane 1: APOBEC3C transfected lysate (22.8kD). Lane 2: Non-transfected lysate.)
Rabbit anti-Human APOBEC3C Polyclonal Antibody
APOBEC3C (APOBEC1L, PBI, DNA dC->dU-editing Enzyme APOBEC-3C, A3C, APOBEC1-like, Phorbolin I)
Reactivity
Human
Applications
Western Blot
Purity
Affinity PurifiedPurified by Protein A affinity chromatography.
Synonyms
APOBEC3C; Polyclonal Antibody; APOBEC3C (APOBEC1L; PBI; DNA dC->dU-editing Enzyme APOBEC-3C; A3C; APOBEC1-like; Phorbolin I); Anti -APOBEC3C (APOBEC1L; anti-APOBEC3C antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human APOBEC3C.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Sequence
MNPQIRNPMKAMYPGTFYFQFKNLWEANDRNETWLCFTVEGIKRRSVVSWKTGVFRNQVDSETHCHAERCFLSWFCDDILSPNTKYQVTWYTSWSPCPDCAGEVAEFLARHSNVNLTIFTARLYYFQYPCYQEGLRSLSQEGVAVEIMDYEDFKYCWENFVYNDNEPFKPWKGLKTNFRLLKRRLRESLQ
Applicable Applications for anti-APOBEC3C antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Immunogen
Full length human APOBEC3C, aa1-190 (NP_055323.2).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western Blot analysis of APOBEC3C expression in transfected 293T cell line by APOBEC3C polyclonal antibody. Lane 1: APOBEC3C transfected lysate (22.8kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of APOBEC3C expression in transfected 293T cell line by APOBEC3C polyclonal antibody. Lane 1: APOBEC3C transfected lysate (22.8kD). Lane 2: Non-transfected lysate.)
Related Product Information for anti-APOBEC3C antibody
DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. Exhibits antiviral activity against simian immunodeficiency virus (SIV), hepatitis B virus (HBV), herpes simplex virus 1 (HHV-1) and Epstein-Barr virus (EBV) and may inhibit the mobility of LTR and non-LTR retrotransposons. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
Product Categories/Family for anti-APOBEC3C antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI Official Full Name
apolipoprotein B editing enzyme catalytic polypeptide-like 3C
Protein Family
Similar Products
Product Notes
The APOBEC3C (Catalog #AAA644836) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The APOBEC3C (APOBEC1L, PBI, DNA dC->dU-editing Enzyme APOBEC-3C, A3C, APOBEC1-like, Phorbolin I) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's APOBEC3C can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the APOBEC3C for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MNPQIRNPMK AMYPGTFYFQ FKNLWEANDR NETWLCFTVE GIKRRSVVSW KTGVFRNQVD SETHCHAERC FLSWFCDDIL SPNTKYQVTW YTSWSPCPDC AGEVAEFLAR HSNVNLTIFT ARLYYFQYPC YQEGLRSLSQ EGVAVEIMDY EDFKYCWENF VYNDNEPFKP WKGLKTNFRL LKRRLRESLQ. It is sometimes possible for the material contained within the vial of "APOBEC3C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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