Western Blot (WB)
(Sample Data: Western blot of rat hippocampal lysate showing specific immunolabeling of the ~115kDa APBA1 protein.)
Rabbit APBA1 Polyclonal Antibody | anti-APBA1 antibody
Anti-APBA1
Reactivity
Human, Mouse, Canine, Chicken, non-Human Primate
Applications
Western Blot
Purity
Affinity Chromatography
Synonyms
APBA1; Polyclonal Antibody; Anti-APBA1; anti-APBA1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Canine, Chicken, non-Human Primate
Clonality
Polyclonal
Isotype
Rabbit, IgG
Specificity
Recognizes the APBA protein
Purity/Purification
Affinity Chromatography
Form/Format
100 ul in 10mM HEPES (pH7.5), 150mMNaCl, 100 ug per ml BSA and 50% glycerol.
Applicable Applications for anti-APBA1 antibody
Western Blot (WB)
Application Notes
WB: 1:1,000
Immunogen
Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH
Preparation and Storage
Store at 4 degree C (add 0.1% NaN3) for several months, and at -20 degree C for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Western Blot (WB)
(Sample Data: Western blot of rat hippocampal lysate showing specific immunolabeling of the ~115kDa APBA1 protein.)
Western Blot (WB)
(Sample Data: Western blot of rat hippocampal lysate showing specific immunolabeling of the ~115kDa APBA1 protein.)
Related Product Information for anti-APBA1 antibody
APBA1 phosphorylates amyloid precursor protein (APP). There is strong evidence that implicates APP in the pathogenesis of Alzheimer's disease (AD)(1). The phosphorylation of APP at Thr668 might be critical for generating soluble APP (beta) and beta-amyloid peptide (abeta) fragments, which are the major components of senile plaques that are found in patient brains inflicted with AD (2,3).
Product Categories/Family for anti-APBA1 antibody
References
1. Liu, F. et al: Regulation of amyloid precursor protein (APP) phosphorylation and processing by p35/cdk5 and p25/cdk5. FEBS Lett 2003 547:193-196.
2. Ando, K. et al: Phosphorylation-dependent regulation of the interaction of amyloid precursor protein with Fe65 affects the production of beta-amyloid. J Biol Chem 2001 276:40353-40361.
3. Kamenetz, F. et al: APP processing and synaptic function. Neuron 2003 37:925-937, 2003.
2. Ando, K. et al: Phosphorylation-dependent regulation of the interaction of amyloid precursor protein with Fe65 affects the production of beta-amyloid. J Biol Chem 2001 276:40353-40361.
3. Kamenetz, F. et al: APP processing and synaptic function. Neuron 2003 37:925-937, 2003.
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Product Notes
The APBA1 (Catalog #AAA515838) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-APBA1 reacts with Human, Mouse, Canine, Chicken, non-Human Primate and may cross-react with other species as described in the data sheet. AAA Biotech's APBA1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:1,000. Researchers should empirically determine the suitability of the APBA1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "APBA1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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