Western Blot (WB)
(Western Blot analysis of C9orf3 expression in transfected 293T cell line by C9orf3 polyclonal antibody. Lane 1: C9orf3 transfected lysate (79.2kD). Lane 2: Non-transfected lysate.)
Mouse anti-Human AOPEP Polyclonal Antibody | anti-C9orf3 antibody
AOPEP (C9orf3, ONPEP, Aminopeptidase O, FLJ14675)
Gene Names
C9orf3; APO; AP-O; AOPEP; ONPEP; C90RF3
Reactivity
Human
Applications
Western Blot
Purity
Affinity PurifiedPurified by Protein A affinity chromatography.
Synonyms
AOPEP; Polyclonal Antibody; AOPEP (C9orf3; ONPEP; Aminopeptidase O; FLJ14675); Anti -AOPEP (C9orf3; anti-C9orf3 antibody
Host
Mouse
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human C9orf3.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Sequence
MDIQLDPARDDLPLMANTSHILVKHYVLDLDVDFESQVIEGTIVLFLEDGNRFKKQNSSIEEACQSESNKACKFGMPEPCHIPVTNARTFSSEMEYNDFAICSKGEKDTSDKDGNHDNQEHASGISSSKYCCDTGNHGSEDFLLVLDCCDLSVLKVEEVDVAAVPGLEKFTRSPELTVVSEEFRNQIVRELVTLPANRWREQLDYYARCSQAPGCGELLFDTDTWSLQIRKTGAQTATDFPHAIRIWYKTKPEGRSVTWTSDQSGRPCVYTVGSPINNRALFPCQEPPVAMSTWQATVRAAASFVVLMSGENSAKPTQLWEECSSWYYYVTMPMPASTFTIAVGCWTEMKMETWSSNDLATERPFSPSEANFRHVGVCSHMEYPCRFQNASATTQEIIPHRVFAPVCLTGACQETLLRLIPPCLSAAHSVLGAHPFSRLDVLIVPANFPSLGMARPSKDKTGHTSDSGASVIKHGLNPEKIFMQVHYLKGYFLLRFLAKRLGDETYFSFLRKFVHTFHGQLILSQDFLQMLLENIPEEKRLELSVENIYQDWLESSGIPKPLQRERRAGAECGLARQVRAEVTKWIGVNRRPRKRKRREKEEVFEKLLPDQLVLLLEHLLEQKTLSPRTLQSLQRTYHLQDQDAEVRHRWCELIVKHKFTKAYKSVERFLQEDQAMGVYLYGELMVSEDARQQQLARRCFERTKEQMDRSSAQVVAEMLF
Applicable Applications for anti-C9orf3 antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Immunogen
Full length human C9orf3, aa1-720 (NP_116212).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western Blot analysis of C9orf3 expression in transfected 293T cell line by C9orf3 polyclonal antibody. Lane 1: C9orf3 transfected lysate (79.2kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of C9orf3 expression in transfected 293T cell line by C9orf3 polyclonal antibody. Lane 1: C9orf3 transfected lysate (79.2kD). Lane 2: Non-transfected lysate.)
Related Product Information for anti-C9orf3 antibody
This gene encodes a member of the M1 zinc aminopeptidase family. The encoded protein is a zinc-dependent metallopeptidase that catalyzes the removal of an amino acid from the amino terminus of a protein or peptide. This protein may play a role in the generation of angiotensin IV. Alternate splicing results in multiple transcript variants.
Product Categories/Family for anti-C9orf3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
93,572 Da
NCBI Official Full Name
aminopeptidase O isoform 4
NCBI Official Synonym Full Names
chromosome 9 open reading frame 3
NCBI Official Symbol
C9orf3
NCBI Official Synonym Symbols
APO; AP-O; AOPEP; ONPEP; C90RF3
NCBI Protein Information
aminopeptidase O
UniProt Protein Name
Aminopeptidase O
UniProt Gene Name
AOPEP
UniProt Synonym Gene Names
C9orf3; ONPEP; AP-O
UniProt Entry Name
AMPO_HUMAN
NCBI Description
This gene encodes a member of the M1 zinc aminopeptidase family. The encoded protein is a zinc-dependent metallopeptidase that catalyzes the removal of an amino acid from the amino terminus of a protein or peptide. This protein may play a role in the generation of angiotensin IV. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010]
Uniprot Description
ONPEP: Aminopeptidases catalyze the hydrolysis of amino acid residues from the N-terminus of peptide or protein substrates. Able to cleave angiotensin III to generate angiotensin IV, a bioactive peptide of the renin-angiotensin pathway. Not able to cleave angiotensin I and angiotensin II. May play a role in the proteolytic processing of bioactive peptides in tissues such as testis and heart. Belongs to the peptidase M1 family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.4.11.-; Protease
Chromosomal Location of Human Ortholog: 9q22.32
Cellular Component: cytoplasm; nucleolus
Molecular Function: metallopeptidase activity; zinc ion binding; aminopeptidase activity
Biological Process: leukotriene biosynthetic process; proteolysis
Research Articles on C9orf3
Similar Products
Product Notes
The C9orf3 aopep (Catalog #AAA6013261) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The AOPEP (C9orf3, ONPEP, Aminopeptidase O, FLJ14675) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's AOPEP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the C9orf3 aopep for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MDIQLDPARD DLPLMANTSH ILVKHYVLDL DVDFESQVIE GTIVLFLEDG NRFKKQNSSI EEACQSESNK ACKFGMPEPC HIPVTNARTF SSEMEYNDFA ICSKGEKDTS DKDGNHDNQE HASGISSSKY CCDTGNHGSE DFLLVLDCCD LSVLKVEEVD VAAVPGLEKF TRSPELTVVS EEFRNQIVRE LVTLPANRWR EQLDYYARCS QAPGCGELLF DTDTWSLQIR KTGAQTATDF PHAIRIWYKT KPEGRSVTWT SDQSGRPCVY TVGSPINNRA LFPCQEPPVA MSTWQATVRA AASFVVLMSG ENSAKPTQLW EECSSWYYYV TMPMPASTFT IAVGCWTEMK METWSSNDLA TERPFSPSEA NFRHVGVCSH MEYPCRFQNA SATTQEIIPH RVFAPVCLTG ACQETLLRLI PPCLSAAHSV LGAHPFSRLD VLIVPANFPS LGMARPSKDK TGHTSDSGAS VIKHGLNPEK IFMQVHYLKG YFLLRFLAKR LGDETYFSFL RKFVHTFHGQ LILSQDFLQM LLENIPEEKR LELSVENIYQ DWLESSGIPK PLQRERRAGA ECGLARQVRA EVTKWIGVNR RPRKRKRREK EEVFEKLLPD QLVLLLEHLL EQKTLSPRTL QSLQRTYHLQ DQDAEVRHRW CELIVKHKFT KAYKSVERFL QEDQAMGVYL YGELMVSEDA RQQQLARRCF ERTKEQMDRS SAQVVAEMLF. It is sometimes possible for the material contained within the vial of "AOPEP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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