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Western Blot (WB) (Western Blot analysis of AOC2 expression in transfected 293T cell line by AOC2 polyclonal antibody. Lane 1: AOC2 transfected lysate (83.7kD). Lane 2: Non-transfected lysate.)

Rabbit anti-Human AOC2 Polyclonal Antibody | anti-AOC2 antibody

AOC2 (Retina-specific Copper Amine Oxidase, RAO, Amine Oxidase [Copper-containing], Semicarbazide-sensitive Amine Oxidase, SSAO)

Gene Names
AOC2; allene oxide cyclase 2; AOC2
Reactivity
Human
Applications
Western Blot
Purity
Affinity Purified
Purified by Protein A affinity chromatography.
Synonyms
AOC2; Polyclonal Antibody; AOC2 (Retina-specific Copper Amine Oxidase; RAO; Amine Oxidase [Copper-containing]; Semicarbazide-sensitive Amine Oxidase; SSAO); Anti -AOC2 (Retina-specific Copper Amine Oxidase; anti-AOC2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human AOC2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Sequence
MHLKIVLAFLALSLITIFALAYVLLTSPGGSSQPPHCPSVSHRAQPWPHPGQSQLFADLSREELTAVMRFLTQRLGPGLVDAAQAQPSDNCIFSVELQLPPKAAALAHLDRGSPPPAREALAIVLFGGQPQPNVSELVVGPLPHPSYMRDVTVERHGGPLPYHRRPVLRAEFTQMWRHLKEVELPKAPIFLSSTFNYNGSTLAAVHATPRGLRSGDRATWMALYHNISGVGLFLHPVGLELLLDHRALDPAHWTVQQVFYLGHYYADLGQLEREFKSGRLEVVRVPLPPPNGASSLRSRNSPGPLPPLQFSPQGSQYSVQGNLVVSSLWSFTFGHGVFSGLRIFDVRFQGERIAYEVSVQECVSIYGADSPKTMLTRYLDSSFGLGRNSRGLVRGVDCPYQATMVDIHILVGKGAVQLLPGAVCVFEEAQGLPLRRHHNYLQNHFYGGLASSALVVRSVSSVGNYDYIWDFVLYPNGALEGRVHATGYINTAFLKGGEEGLLFGNRVGERVLGTVHTHAFHFKLDLDVAGLKNWVVAEDVVFKPVAAPWNPEHWLQRPQLTRQVLGKEDLTAFSLGSPLPRYLYLASNQTNAWGHQRGYRIQIHSPLGIHIPLESDMERALSWGRYQLVVTQRKEEESQSSSIYHQNDIWTPTVTFADFINNETLLGEDLVAWVTASFLHIPHAEDIPNTVTLGNRVGFLLRPYNFFDEDPSIFSPGSVYFEKGQDAGLCSINPVACLPDLAACVPDLPPFSYHGF
Applicable Applications for anti-AOC2 antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Immunogen
Full length human AOC2, aa1-756 (NP_033720.2).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of AOC2 expression in transfected 293T cell line by AOC2 polyclonal antibody. Lane 1: AOC2 transfected lysate (83.7kD). Lane 2: Non-transfected lysate.)

Western Blot (WB) (Western Blot analysis of AOC2 expression in transfected 293T cell line by AOC2 polyclonal antibody. Lane 1: AOC2 transfected lysate (83.7kD). Lane 2: Non-transfected lysate.)
Related Product Information for anti-AOC2 antibody
AOC2 (Amine oxidase, copper containing 2) belongs to the copper/topaquinone oxidase family. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine.
Product Categories/Family for anti-AOC2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
27,635 Da
NCBI Official Full Name
allene oxide cyclase 2
NCBI Official Symbol
AOC2
NCBI Official Synonym Symbols
allene oxide cyclase 2; AOC2
NCBI Protein Information
allene oxide cyclase 2
UniProt Protein Name
Allene oxide cyclase 2, chloroplastic
Protein Family
UniProt Gene Name
AOC2
UniProt Entry Name
AOC2_ARATH

NCBI Description

Encodes allene oxide cyclase. One of four genes in Arabidopsis that encode this enzyme, which catalyzes an essential step in jasmonic acid biosynthesis. Gene expression is induced during senescence, a process that involves jasmonic acid signalling pathway. Note: Nomenclature for Arabidopsis allene oxide cyclase 2 (AOC2, AT3G25770) gene is based on Stenzel et al. 2003 Plant Molecular Biology 51:895-911. AOC2 (AT3G25770) is also referred to as AOC3 in He et al. 2002 Plant Physiology, 128:876-884.

Uniprot Description

Function: Involved in the production of 12-oxo-phytodienoic acid (OPDA), a precursor of jasmonic acid.

Catalytic activity: (9Z)-(13S)-12,13-epoxyoctadeca-9,11,15-trienoate = (15Z)-12-oxophyto-10,15-dienoate.

Subcellular location: Plastid › chloroplast Ref.1.

Tissue specificity: Highly expressed in fully developed leaves. Ref.1

Induction: High local and systemic induction by wounding. Ref.1

Miscellaneous: The four allene oxide cyclase proteins (AOC1, AOC2, AOC3 and AOC4) are encoded by duplicated genes. They are very similar, and most experiments involving antibodies do not discriminate between the different members.

Sequence similarities: Belongs to the allene oxide cyclase family.

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Product Notes

The AOC2 aoc2 (Catalog #AAA6012346) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AOC2 (Retina-specific Copper Amine Oxidase, RAO, Amine Oxidase [Copper-containing], Semicarbazide-sensitive Amine Oxidase, SSAO) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's AOC2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the AOC2 aoc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MHLKIVLAFL ALSLITIFAL AYVLLTSPGG SSQPPHCPSV SHRAQPWPHP GQSQLFADLS REELTAVMRF LTQRLGPGLV DAAQAQPSDN CIFSVELQLP PKAAALAHLD RGSPPPAREA LAIVLFGGQP QPNVSELVVG PLPHPSYMRD VTVERHGGPL PYHRRPVLRA EFTQMWRHLK EVELPKAPIF LSSTFNYNGS TLAAVHATPR GLRSGDRATW MALYHNISGV GLFLHPVGLE LLLDHRALDP AHWTVQQVFY LGHYYADLGQ LEREFKSGRL EVVRVPLPPP NGASSLRSRN SPGPLPPLQF SPQGSQYSVQ GNLVVSSLWS FTFGHGVFSG LRIFDVRFQG ERIAYEVSVQ ECVSIYGADS PKTMLTRYLD SSFGLGRNSR GLVRGVDCPY QATMVDIHIL VGKGAVQLLP GAVCVFEEAQ GLPLRRHHNY LQNHFYGGLA SSALVVRSVS SVGNYDYIWD FVLYPNGALE GRVHATGYIN TAFLKGGEEG LLFGNRVGER VLGTVHTHAF HFKLDLDVAG LKNWVVAEDV VFKPVAAPWN PEHWLQRPQL TRQVLGKEDL TAFSLGSPLP RYLYLASNQT NAWGHQRGYR IQIHSPLGIH IPLESDMERA LSWGRYQLVV TQRKEEESQS SSIYHQNDIW TPTVTFADFI NNETLLGEDL VAWVTASFLH IPHAEDIPNT VTLGNRVGFL LRPYNFFDED PSIFSPGSVY FEKGQDAGLC SINPVACLPD LAACVPDLPP FSYHGF. It is sometimes possible for the material contained within the vial of "AOC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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