Rabbit ANP32D Polyclonal Antibody | anti-ANP32D antibody

ANP32D Polyclonal Antibody

Cat. Num. AAA3006331

• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: ANP32D; Polyclonal Antibody; ANP32D Polyclonal Antibody; cidic leucine-rich nuclear phosphoprotein 32 family member D; Phosphoprotein 32-related protein 2; Tumorigenic protein pp32r2; PP32R2; anti-ANP32D antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: ANP32D polyclonal antibody detects endogenous levels of ANP32D protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 131

• Applicable Applications for anti-ANP32D antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: A synthetic peptide corresponding to residues in Human ANP32D.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of ANP32D polyclonal antibody at 1:500 dilutionLane1:Hela whole cell lysateLane2:Mouse liver tissue lysateLane3:Rat iver tissue lysate)

Related Product Information for anti-ANP32D antibody

ANP32D (acidic (leucine-rich) nuclear phosphoprotein 32 family, member D), also known as PP32R2 (phosphoprotein 32-related protein 2) or tumorigenic protein pp32r2, is a 131 amino acid protein that contains 3 leucine-rich repeats and belongs to the ANP32 family. ANP32D shares 89.3% amino acid sequence identity with ANP32A, a tumor suppressor that inhibits a variety of cancers, such as prostate and breast cancers. Although similar to ANP32A, ANP32D is tumorigenic and is preferentially expressed in prostatic cancer. Conversely, it is uncertain that ANP32D is neurally expressed. Intronless, ANP32D may be a pseudogene that is expressed in pathological situations and may also modulate the oncogenic potential of human prostate cancer. A

NCBI and Uniprot Product Information

• NCBI GI #: 21071028
• NCBI Accession #: NP_036536.2
• NCBI GenBank Nucleotide #: NP_036536.2
• UniProt Accession #: O95626
• Molecular Weight: ~ 15kDa
• NCBI Official Full Name: acidic leucine-rich nuclear phosphoprotein 32 family member D
• UniProt Protein Name: Acidic leucine-rich nuclear phosphoprotein 32 family member D
• Protein Family: Acidic leucine-rich nuclear phosphoprotein 32 family
• UniProt Gene Name: ANP32D
• UniProt Synonym Gene Names: PP32R2
• UniProt Entry Name: AN32D_HUMAN

Uniprot Description

ANP32D: Phosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is absent in the protein encoded by this gene. This gene does not contain introns. [provided by RefSeq, Jul 2008]

Chromosomal Location of Human Ortholog: 12q13.11