Rabbit ANP32B Polyclonal Antibody | anti-ANP32B antibody

ANP32B (Acidic Leucine-rich Nuclear Phosphoprotein 32 Family Member B, APRIL, SSP29, PHAPI2, Putative HLA-DR-associated Protein I-2) (APC)

Cat. Num. AAA6406532

• Gene Names: ANP32B; APRIL; SSP29; PHAPI2
• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry, Western Blot, Immunoprecipitation
• Purity: Purified by affinity chromatography.
• Synonyms: ANP32B; Polyclonal Antibody; ANP32B (Acidic Leucine-rich Nuclear Phosphoprotein 32 Family Member B; APRIL; SSP29; PHAPI2; Putative HLA-DR-associated Protein I-2) (APC); anti-ANP32B antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes ANP32B. Species Crossreactivity: human, mouse, rat
• Purity/Purification: Purified by affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
• Concentration: ~1mg/ml (varies by lot)

• Applicable Applications for anti-ANP32B antibody: Immunohistochemistry (IHC), Western Blot (WB), Immunoprecipitation (IP)
• Application Notes: IHC: 1:50-1:200; WB: 1:500-1:2000; IP: 1:20-1:50; Applications are based on unconjugated antibody.
• Immunogen: Recombinant protein corresponding to human ANP32B.
• Conjugate: APC
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Product Categories/Family for anti-ANP32B antibody

Antibodies; Apoptosis

NCBI and Uniprot Product Information

• NCBI GI #: 5454088
• NCBI GeneID: 10541
• NCBI Accession #: NP_006392.1
• NCBI GenBank Nucleotide #: NM_006401.2
• UniProt Accession #: Q92688; O00655; P78458; P78459; B2R9C7
• Molecular Weight: 28,788 Da
• NCBI Official Full Name: acidic leucine-rich nuclear phosphoprotein 32 family member B
• NCBI Official Synonym Full Names: acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
• NCBI Official Symbol: ANP32B
• NCBI Official Synonym Symbols: APRIL; SSP29; PHAPI2
• NCBI Protein Information: acidic leucine-rich nuclear phosphoprotein 32 family member B; silver-stainable protein SSP29; acidic protein rich in leucines; putative HLA-DR-associated protein I-2
• UniProt Protein Name: Acidic leucine-rich nuclear phosphoprotein 32 family member B
• Protein Family: Acidic leucine-rich nuclear phosphoprotein 32 family
• UniProt Gene Name: ANP32B
• UniProt Synonym Gene Names: APRIL; PHAPI2; PHAPI2
• UniProt Entry Name: AN32B_HUMAN

Uniprot Description

ANP32B: Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity. Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome. Belongs to the ANP32 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 9q22.32

Cellular Component: cytoplasm; nucleolus; nucleus

Molecular Function: histone binding

Biological Process: positive regulation of protein export from nucleus; caspase activation; nucleosome assembly; negative regulation of cell differentiation; vasculature development; ventricular system development; palate development; inner ear development