Western Blot (WB)
(Anti-Annexin A3 antibody, MBS175431, Western blottingAll lanes: Anti Annexin A3 (MBS175431) at 0.5ug/mlLane 1: Rat Brain Tissue Lysate at 50ugLane 2: Rat Testis Tissue Lysate at 50ugLane 3: Rat Skeletal Muscle Tissue Lysate at 50ugLane 4: Rat Lung Tissue Lysate at 50ugLane 5: SW620 Whole Cell Lysate at 40ugLane 6: HELA Whole Cell Lysate at 40ugLane 7: SMMC Whole Cell Lysate at 40ugLane 8: MCF-7 Whole Cell Lysate at 40ugPredicted bind size: 36KDObserved bind size: 36KD )
Rabbit Annexin A3 Polyclonal Antibody | anti-ANXA3 antibody
Anti-Annexin A3 antibody
Western Blot (WB)
(Anti-Annexin A3 antibody, MBS175431, Western blottingAll lanes: Anti Annexin A3 (MBS175431) at 0.5ug/mlLane 1: Rat Brain Tissue Lysate at 50ugLane 2: Rat Testis Tissue Lysate at 50ugLane 3: Rat Skeletal Muscle Tissue Lysate at 50ugLane 4: Rat Lung Tissue Lysate at 50ugLane 5: SW620 Whole Cell Lysate at 40ugLane 6: HELA Whole Cell Lysate at 40ugLane 7: SMMC Whole Cell Lysate at 40ugLane 8: MCF-7 Whole Cell Lysate at 40ugPredicted bind size: 36KDObserved bind size: 36KD )
Western Blot (WB)
(Anti-Annexin A3 antibody, MBS175431, Western blottingAll lanes: Anti Annexin A3 (MBS175431) at 0.5ug/mlLane 1: Rat Brain Tissue Lysate at 50ugLane 2: Rat Testis Tissue Lysate at 50ugLane 3: Rat Skeletal Muscle Tissue Lysate at 50ugLane 4: Rat Lung Tissue Lysate at 50ugLane 5: SW620 Whole Cell Lysate at 40ugLane 6: HELA Whole Cell Lysate at 40ugLane 7: SMMC Whole Cell Lysate at 40ugLane 8: MCF-7 Whole Cell Lysate at 40ugPredicted bind size: 36KDObserved bind size: 36KD )
Immunohistochemistry (IHC)
(Anti-Annexin A3 antibody, MBS175431, IHC(P)IHC(P): Human Mammary Cancer Tissue )
Immunohistochemistry (IHC)
(Anti-Annexin A3 antibody, MBS175431, IHC(P)IHC(P): Human Mammary Cancer Tissue )
Background: Annexin A3 is a protein that in humans is encoded by the Annexin A3 gene. The Annexin A3 gene contains 13 exons and spans 58 kb of genomic DNA. The Annexin A3 gene is mapped to 4q21. It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART. This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phospholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.
NCBI and Uniprot Product Information
NCBI Description
inhibits phospholipase A2 activity [RGD, Feb 2006]
Uniprot Description
ANXA3: a calcium/phospholipid-binding protein and inhibitor of phospholipase A2, Possesses anti-coagulant properties. Cleaves the cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. Annexins are a family of structurally related proteins whose common property is calcium-dependent binding to phospholipids. There are at least ten different annexins in mammalian species. Annexins do not contain signal peptides, yet some annexins (A1, A2 and A5) appear to be secreted in a physiologically regulated fashion.
Protein type: Calcium-binding
Cellular Component: specific granule; phagocytic vesicle membrane; membrane; cell soma; axon; cytoplasm; dendrite; plasma membrane
Molecular Function: phospholipase inhibitor activity; calcium-dependent phospholipid binding; phospholipase A2 inhibitor activity; calcium ion binding; calcium-dependent protein binding
Biological Process: positive regulation of DNA metabolic process; organ regeneration; positive regulation of angiogenesis; hippocampus development; response to glucocorticoid stimulus; negative regulation of catalytic activity; defense response to bacterium; neutrophil degranulation; positive regulation of transcription factor activity; phagocytosis
Research Articles on ANXA3
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Product Notes
The ANXA3 anxa3 (Catalog #AAA175431) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Annexin A3 antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Annexin A3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin. Researchers should empirically determine the suitability of the ANXA3 anxa3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Annexin A3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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