Immunofluorescence (IF)
(Immunofluorescence analysis of HeLa cell using ANLN antibody. Blue: DAPI for nuclear staining.)
Rabbit anti-Human ANLN Polyclonal Antibody | anti-ANLN antibody
ANLN antibody
Gene Names
ANLN; scra; FSGS8; Scraps
Reactivity
Human
Applications
Western Blot, Immunofluorescence
Purity
Antibodies were purified by affinity purification using immunogen.
Synonyms
ANLN; Polyclonal Antibody; ANLN antibody; scra; FSGS8; Scraps; anti-ANLN antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total ANLN antibody.
Purity/Purification
Antibodies were purified by affinity purification using immunogen.
Form/Format
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
1087
Applicable Applications for anti-ANLN antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes
Western blotting: 1:500 - 1:2000
Immunofluorescence: 1:50 - 1:100
Immunofluorescence: 1:50 - 1:100
Immunogen Type
Recombinant Protein
Immunogen Description
Recombinant protein of human ANLN.
Target Name
ANLN
Preparation and Storage
Store at -20 degree C
Immunofluorescence (IF)
(Immunofluorescence analysis of HeLa cell using ANLN antibody. Blue: DAPI for nuclear staining.)
Immunofluorescence (IF)
(Immunofluorescence analysis of HeLa cell using ANLN antibody. Blue: DAPI for nuclear staining.)
Related Product Information for anti-ANLN antibody
This gene encodes an actin-binding protein that plays a role in cell growth and migration, and in cytokinesis. The encoded protein is thought to regulate actin cytoskeletal dynamics in podocytes, components of the glomerulus. Mutations in this gene are associated with focal segmental glomerulosclerosis 8. Alternative splicing results in multiple transcript variants encoding different isoforms.
Product Categories/Family for anti-ANLN antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
120,016 Da
NCBI Official Full Name
actin-binding protein anillin isoform 2
NCBI Official Synonym Full Names
anillin actin binding protein
NCBI Official Symbol
ANLN
NCBI Official Synonym Symbols
scra; FSGS8; Scraps
NCBI Protein Information
actin-binding protein anillin
UniProt Protein Name
Actin-binding protein anillin
Protein Family
UniProt Gene Name
ANLN
UniProt Entry Name
ANLN_HUMAN
NCBI Description
This gene encodes an actin-binding protein that plays a role in cell growth and migration, and in cytokinesis. The encoded protein is thought to regulate actin cytoskeletal dynamics in podocytes, components of the glomerulus. Mutations in this gene are associated with focal segmental glomerulosclerosis 8. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]
Uniprot Description
Required for cytokinesis (PubMed:16040610). Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression. May play a significant role in podocyte cell migration (PubMed:24676636).
Research Articles on ANLN
Similar Products
Product Notes
The ANLN anln (Catalog #AAA9403491) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ANLN antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ANLN can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF). Western blotting: 1:500 - 1:2000 Immunofluorescence: 1:50 - 1:100. Researchers should empirically determine the suitability of the ANLN anln for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ANLN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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