Rabbit ANGPTL2 Polyclonal Antibody | anti-ANGPTL2 antibody

ANGPTL2 (Angiopoietin-like Protein 2)

Cat. Num. AAA644499

• Gene Names: ANGPTL2; ARP2; HARP
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: ANGPTL2; Polyclonal Antibody; ANGPTL2 (Angiopoietin-like Protein 2); Anti -ANGPTL2 (Angiopoietin-like Protein 2); anti-ANGPTL2 antibody

• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Recognizes the fibrinogen-like domain of human ANGPTL2. Detects a band of ~57kD by Western blot. Cross-reacts with full-length human ANGPTL2.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in 0.2um-filtered PBS, pH 7.4. No preservative added.

• Applicable Applications for anti-ANGPTL2 antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in ELISA, Western Blot
• Immunogen: Recombinant human ANGPTL2.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western blot analysis using anti-ANGPTL2 (human), pAb at 1:2'000 dilution. 1: Human ANGPTL2 (DYKDDDDK-tagged). 2: Human ANGPTL2 (FLD) (DYKDDDDK-tagged). 3: Human ANGPTL4 (DYKDDDDK-tagged). 4: Human ANGPTL6 (DYKDDDDK-tagged). 5: Human ANGPTL7 (DYKDDDDK-tagged). 6: Human ANGPTL3 (FLD) (DYKDDDDK-tagged). 7: Human ANGPTL7 (FLD) (DYKDDDDK-tagged). 8: Human ANGPTL4 (FLD) (DYKDDDDK-tagged).)

Related Product Information for anti-ANGPTL2 antibody

ANGPTL2 stimulates expansion of HSCs. ANGPTL2 plays an important role in the pathogenesis of diabetic glomerulopathy. The upregulation of ANGPTL2 in diabetic glomerulopathy shows a close relationship to abnormal microvasculature and endothelial inflammation.

Product Categories/Family for anti-ANGPTL2 antibody

Antibodies; Abs to Angiopoietin

NCBI and Uniprot Product Information

• NCBI GI #: 6912236
• NCBI GeneID: 23452
• NCBI Accession #: NP_036230.1
• NCBI GenBank Nucleotide #: NM_012098.2
• UniProt Accession #: Q9UKU9; Q5JT58
• Molecular Weight: 57,104 Da
• NCBI Official Full Name: angiopoietin-related protein 2
• NCBI Official Synonym Full Names: angiopoietin-like 2
• NCBI Official Symbol: ANGPTL2
• NCBI Official Synonym Symbols: ARP2; HARP
• NCBI Protein Information: angiopoietin-related protein 2; angiopoietin-like protein 2
• UniProt Protein Name: Angiopoietin-related protein 2
• Protein Family: Angiopoietin-related protein
• UniProt Gene Name: ANGPTL2
• UniProt Synonym Gene Names: ARP2
• UniProt Entry Name: ANGL2_HUMAN

NCBI Description

Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 protein is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action. [provided by RefSeq, Jul 2008]

Uniprot Description

ANGPTL2: Induces sprouting in endothelial cells through an autocrine and paracrine action.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 9q34

Cellular Component: extracellular space

Molecular Function: receptor binding

Biological Process: multicellular organismal development