Rabbit AMPK alpha 1 Polyclonal Antibody | anti-AMPKalpha1 antibody

Anti-AMPK alpha 1

Cat. Num. AAA516153

• Reactivity: Western blot human AMPKa1; AMPK1 from other species may also be detectable.
• Applications: Western Blot
• Purity: Affinity chromatography
• Synonyms: AMPK alpha 1; Polyclonal Antibody; Anti-AMPK alpha 1; anti-AMPKalpha1 antibody

• Host: Rabbit
• Reactivity: Western blot human AMPKa1; AMPK1 from other species may also be detectable.
• Clonality: Polyclonal
• Specificity: Recognizes the AMPKalpha1 protein
• Purity/Purification: Affinity chromatography
• Form/Format: PBS pH7.4, 0.02% sodium azide, 50% glycerol

• Applicable Applications for anti-AMPKalpha1 antibody: Western Blot (WB)
• Application Notes: WB: 22138:23137
• Immunogen: Synthetic peptide corresponding to amino acids 483-487 of human AMPKalpha
• Preparation and Storage: Store at 4 degree C (add 0.1% NaN3) for several months, and at -20 degree C for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For optimal performance, avoid repeated handling and multiple freeze/thaw cycles.

Western Blot (WB)

(Sample Data: Representative western blot with Anti-AMPK1alpha (1:1000) using 20 ng of human recombinant AMPK1 and AMPK2.)

Related Product Information for anti-AMPKalpha1 antibody

AMP-activated protein kinase (AMPK) exhibits a key role as a master regulator of cellular energy homeostasis (1). AMPK exists as a heterotrimeric complex composed of a catalytic alpha subunit and regulatory beta and gamma subunits. Binding of AMP to the gamma subunit allosterically activates the complex. AMPK is activated in response to stresses that deplete cellular ATP (low glucose, hypoxia and ischemia)(2) and via signaling pathways in response to adiponectin, leptin and CAMKKbeta.

Product Categories/Family for anti-AMPKalpha1 antibody

Isoform Specific Antibodies; Apoptosis/Autophagy; Cancer; Cellular Stress; Metabolic Disorder; Ser/Thr Kinases

References

1. Hardie, G.D. The AMP-activated protein kinase pathway -new players upstream and downstream. J. Cell Sci. 2004;117: 5479-5487.
2. Kahn, B.B. et al. AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism. Cell Metab; 2005: 1, 15-25.