Goat Amisyn / STXBP6 Polyclonal Antibody | anti-STXBP6 antibody

Goat Polyclonal to Human Amisyn / STXBP6

Cat. Num. AAA242201

• Gene Names: STXBP6; amisyn; HSPC156
• Reactivity: Gibbon, Bovine, Gorilla, Horse, Human, Monkey, Mouse, Pig, Rabbit; Predicted Reactivity: Bat (at least 90% immunogen sequence identity)
• Applications: Immunohistochemistry, ELISA
• Purity: Immunoaffinity Purified
• Synonyms: Amisyn / STXBP6; Polyclonal Antibody; Goat Polyclonal to Human Amisyn / STXBP6; Anti-Amisyn / STXBP6 Antibody (N-Terminus) IHC-plus; Amisyn; HSPC156; Syntaxin-binding protein 6; Human Amisyn; STXBP6; anti-STXBP6 antibody

• Host: Goat
• Reactivity: Gibbon, Bovine, Gorilla, Horse, Human, Monkey, Mouse, Pig, Rabbit; Predicted Reactivity: Bat (at least 90% immunogen sequence identity)
• Clonality: Polyclonal
• Specificity: Human STXBP6.
• Purity/Purification: Immunoaffinity Purified
• Form/Format: Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
• Concentration: 0.5 mg/ml (varies by lot)
• Sequence Length: 210

• Applicable Applications for anti-STXBP6 antibody: Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
• Application Notes: ELISA (1:32000), IHC-P (3.75 ug/ml); Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
• Target Species: Human
• Immunogen Description: Synthetic peptide SAKSAISKEIFAP-C from the N-terminus of human STXBP6 (NP_054897.4). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Elephant, Bovine, Horse, Rabbit, Pig (100%); Bat, Opossum, Platypus (92%).
• Immunogen Type: Synthetic peptide
• Immunogen: Amisyn / STXBP6 antibody was raised against synthetic peptide SAKSAISKEIFAP-C from the N-terminus of human STXBP6 (NP_054897.4). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Elephant, Bovine, Horse, Rabbit, Pig (100%); Bat, Opossum, Platypus (92%); Chicken (85%).
• Antigen Modification: N-Terminus
• Preparation and Storage: Store at -20 degree C. Minimize freezing and thawing.

Immunohistochemistry (IHC)

(Anti-STXBP6 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 75 ug/ml.)

NCBI and Uniprot Product Information

• NCBI GI #: 21426793
• NCBI GeneID: 29091
• NCBI Accession #: NP_054897.4
• NCBI GenBank Nucleotide #: NM_014178.6
• UniProt Accession #: Q8NFX7; Q8N3H1; Q8N8D5; Q96GF3; Q9P008; D3DS78
• Molecular Weight: 11,587 Da
• NCBI Official Full Name: syntaxin-binding protein 6
• NCBI Official Synonym Full Names: syntaxin binding protein 6 (amisyn)
• NCBI Official Symbol: STXBP6
• NCBI Official Synonym Symbols: amisyn; HSPC156
• NCBI Protein Information: syntaxin-binding protein 6
• UniProt Protein Name: Syntaxin-binding protein 6
• Protein Family: Syntaxin-binding protein
• UniProt Gene Name: STXBP6
• UniProt Entry Name: STXB6_HUMAN

NCBI Description

STXBP6 binds components of the SNARE complex (see MIM 603215) and may be involved in regulating SNARE complex formation (Scales et al., 2002 [PubMed 12145319]).[supplied by OMIM, Mar 2008]

Uniprot Description

STXBP6: Forms non-fusogenic complexes with SNAP25 and STX1A and may thereby modulate the formation of functional SNARE complexes and exocytosis. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 14q12

Cellular Component: cytoplasm; integral to membrane

Biological Process: vesicle-mediated transport; negative regulation of exocytosis