Testing Data
Rabbit AMICA1 Polyclonal Antibody | anti-AMICA1 antibody
AMICA1 Antibody
Gene Names
JAML; AMICA; Gm638; AMICA1; CREA7-1; CREA7-4
Reactivity
HumanPredicted: Mouse, Rat
Applications
ELISA, Western Blot
Synonyms
AMICA1; Polyclonal Antibody; AMICA1 Antibody; anti-AMICA1 antibody
Host
Rabbit
Reactivity
Human
Predicted: Mouse, Rat
Predicted: Mouse, Rat
Clonality
Polyclonal
Form/Format
Purified by protein affinity column containing 1% BSA and 0.02% NaN3
Sequence Length
1607
Applicable Applications for anti-AMICA1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
ELISA: 1:20,000-1:80,000
WB: 1:500-1:1,000
WB: 1:500-1:1,000
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
Testing Data
Testing Data
Related Product Information for anti-AMICA1 antibody
Rabbit polyclonal AMICA1 (1) antibody was raised against a recombinate human AMICA1 protein 6-235aa (BC100797).
Product Categories/Family for anti-AMICA1 antibody
References
(1) Rose, J.E., Behm, F.M., Drgon, T., et al. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.Mol. Med. 16 (7-8), 247-253 (2010).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
40,136 Da
NCBI Official Full Name
Homo sapiens adhesion molecule, interacts with CXADR antigen 1, mRNA
NCBI Official Synonym Full Names
junction adhesion molecule like
NCBI Official Symbol
JAML
NCBI Official Synonym Symbols
AMICA; Gm638; AMICA1; CREA7-1; CREA7-4
NCBI Protein Information
junctional adhesion molecule-like
UniProt Protein Name
Junctional adhesion molecule-like
UniProt Gene Name
JAML
Uniprot Description
Transmembrane protein of the plasma membrane of leukocytes that control their migration and activation through interaction with CXADR, a plasma membrane receptor found on adjacent epithelial and endothelial cells. The interaction between both receptors mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair. It also controls the transmigration of leukocytes within epithelial and endothelial tissues through adhesive interactions with epithelial and endothelial CXADR.
Research Articles on AMICA1
Similar Products
Product Notes
The AMICA1 jaml (Catalog #AAA854144) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AMICA1 Antibody reacts with Human Predicted: Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's AMICA1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: 1:20,000-1:80,000 WB: 1:500-1:1,000. Researchers should empirically determine the suitability of the AMICA1 jaml for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AMICA1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
