Rabbit anti-Human AMH Polyclonal Antibody | anti-AMH antibody

AMH Antibody

Cat. Num. AAA9405430

• Gene Names: AMH; MIF; MIS
• Reactivity: Human
• Applications: Immunohistochemistry
• Purity: Antigen affinity purification.
• Synonyms: AMH; Polyclonal Antibody; AMH Antibody; MIF; MIS; anti-AMH antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: The antibody detects endogenous levels of total AMH protein.
• Purity/Purification: Antigen affinity purification.
• Form/Format: Supplied in pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 560

• Applicable Applications for anti-AMH antibody: Immunohistochemistry (IHC)
• Application Notes: Immunohistochemistry: 1:25-1:100
• Immunogen Type: Peptide
• Immunogen Description: Synthetic peptide corresponding to residues near the C terminal of human anti-Mullerian hormone
• Target Name: AMH
• Preparation and Storage: Store at -20 degree C

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human brain tissue using MBS9405430 at dilution 1/25.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using MBS9405430 at dilution 1/25.)

Related Product Information for anti-AMH antibody

Anti-Mullerian hormone is a member of the transforming growth factor-beta gene family which mediates male sexual differentiation. Anti-Mullerian hormone causes the regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes. Some mutations in the anti-Mullerian hormone result in persistent Mullerian duct syndrome.

Product Categories/Family for anti-AMH antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 157266298
• NCBI GeneID: 268
• NCBI Accession #: NP_000470.2
• NCBI GenBank Nucleotide #: NM_000479.3
• UniProt Accession #: P03971; O75246; Q6GTN3
• NCBI Official Full Name: muellerian-inhibiting factor
• NCBI Official Synonym Full Names: anti-Mullerian hormone
• NCBI Official Symbol: AMH
• NCBI Official Synonym Symbols: MIF; MIS
• NCBI Protein Information: muellerian-inhibiting factor
• UniProt Protein Name: Muellerian-inhibiting factor
• Protein Family: Muellerian-inhibiting factor
• UniProt Gene Name: AMH
• UniProt Synonym Gene Names: MIF; AMH; MIS
• UniProt Entry Name: MIS_HUMAN

NCBI Description

Anti-Mullerian hormone is a member of the transforming growth factor-beta gene family which mediates male sexual differentiation. Anti-Mullerian hormone causes the regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes. Some mutations in the anti-Mullerian hormone result in persistent Mullerian duct syndrome. [provided by RefSeq, Jul 2008]

Uniprot Description

AMH: This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin. Defects in AMH are the cause of persistent Muellerian duct syndrome type 1 (PMDS1). PMDS1 is a form of male pseudohermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males. Belongs to the TGF-beta family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: extracellular space; cytoplasm; extracellular region

Molecular Function: growth factor activity; hormone activity; transforming growth factor beta receptor binding; receptor binding

Biological Process: response to drug; sex determination; Mullerian duct regression; cell-cell signaling; preantral ovarian follicle growth; gonadal mesoderm development; response to organic cyclic substance; sex differentiation; urogenital system development; activation of NF-kappaB transcription factor; aging

Disease: Persistent Mullerian Duct Syndrome, Types I And Ii