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Testing Data

Rabbit anti-Human AMH Polyclonal Antibody | anti-AMH antibody

AMH Antibody

Gene Names
AMH; MIF; MIS
Reactivity
Human
Applications
ELISA, Western Blot
Synonyms
AMH; Polyclonal Antibody; AMH Antibody; anti-AMH antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Form/Format
Purified by protein A column containing 0.02% NaN3.
Sequence Length
560
Applicable Applications for anti-AMH antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes
Peptide ELISA: 1:10,000-1:40,000
WB: 1:1,000-1:2,000
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C.

Testing Data

Testing Data
Related Product Information for anti-AMH antibody
Rabbit polyclonal AMH(1) antibody was raised against a 16 amino acid peptide from near the C terminal residues of human AMH protein.
References
(1) Legeai, L., Lefevre, G., Vigier, B.et, al A monoclonal antibody against human testicular anti-mullerian hormone Am J Reprod Immunol Microbiol.1988; 18(2):39-43.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
268
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
59,195 Da
NCBI Official Full Name
muellerian-inhibiting factor preproprotein
NCBI Official Synonym Full Names
anti-Mullerian hormone
NCBI Official Symbol
AMH
NCBI Official Synonym Symbols
MIF; MIS
NCBI Protein Information
muellerian-inhibiting factor
UniProt Protein Name
Muellerian-inhibiting factor
UniProt Gene Name
AMH
UniProt Synonym Gene Names
MIF; AMH; MIS

NCBI Description

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome. [provided by RefSeq, Jul 2016]

Uniprot Description

This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin.

Research Articles on AMH

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Product Notes

The AMH amh (Catalog #AAA852111) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AMH Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's AMH can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA: 1:10,000-1:40,000 WB: 1:1,000-1:2,000. Researchers should empirically determine the suitability of the AMH amh for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AMH, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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