Rabbit anti-Human ALS2CR8 Polyclonal Antibody | anti-ALS2CR8 antibody

ALS2CR8, NT (ALS2CR8, CARF, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein, Calcium-response factor, Testis development protein NYD-SP24) (PE)

Cat. Num. AAA6273102

• Gene Names: CARF; ALS2CR8; NYD-SP24
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: ALS2CR8; Polyclonal Antibody; NT (ALS2CR8; CARF; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein; Calcium-response factor; Testis development protein NYD-SP24) (PE); Testis development protein NYD-SP24; anti-ALS2CR8 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-ALS2CR8 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: ALS2CR8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-158 amino acids from the N-terminal region of human ALS2CR8.
• Conjugate: PE
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(ALS2CR8 Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ALS2CR8 antibody detected the ALS2CR8 protein (arrow).)

Related Product Information for anti-ALS2CR8 antibody

ALS2CR8 may be a transcription factor (By similarity).

Product Categories/Family for anti-ALS2CR8 antibody

Antibodies; Disease Markers

References

Cheung, C.T., et al. Mech. Ageing Dev. 130 (1-2), 18-23 (2009): Hillier, L.W., et al. Nature 434(7034):724-731(2005). Hasan, M.K., et al. J. Biol. Chem. 277(40):37765-37770(2002). Tao, X., et al. Neuron 33(3):383-395(2002). Hadano, S., et al. Nat. Genet. 29(2):166-173(2001).

NCBI and Uniprot Product Information

• NCBI GI #: 157168372
• NCBI GeneID: 79800
• NCBI Accession #: NP_001098056.1
• NCBI GenBank Nucleotide #: NM_001104586.1
• UniProt Accession #: Q8N187; Q8ND29; Q8WXC0; Q96J78; Q96Q38; Q96Q39; Q9H712
• Molecular Weight: 80,698 Da
• NCBI Official Full Name: amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein
• NCBI Official Synonym Full Names: calcium responsive transcription factor
• NCBI Official Symbol: CARF
• NCBI Official Synonym Symbols: ALS2CR8; NYD-SP24
• NCBI Protein Information: amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein; calcium-response factor; testis development protein NYD-SP24; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 8
• UniProt Protein Name: Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein
• UniProt Gene Name: ALS2CR8
• UniProt Synonym Gene Names: CARF; CaRF
• UniProt Entry Name: AL2S8_HUMAN

Uniprot Description

CARF: May be a transcription factor. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 2q33.2

Cellular Component: nucleoplasm; nucleolus; nucleus

Molecular Function: DNA binding; transcription factor activity

Biological Process: transcription, DNA-dependent