Rabbit anti-Human ALS2CR8 Polyclonal Antibody | anti-ALS2CR8 antibody

ALS2CR8, NT (ALS2CR8, CARF, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein, Calcium-response factor, Testis development protein NYD-SP24) (Biotin)

Cat. Num. AAA6273094

• Gene Names: CARF; ALS2CR8; NYD-SP24
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: ALS2CR8; Polyclonal Antibody; NT (ALS2CR8; CARF; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein; Calcium-response factor; Testis development protein NYD-SP24) (Biotin); Testis development protein NYD-SP24; anti-ALS2CR8 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-ALS2CR8 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: ALS2CR8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-158 amino acids from the N-terminal region of human ALS2CR8.
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(ALS2CR8 Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ALS2CR8 antibody detected the ALS2CR8 protein (arrow).)

Related Product Information for anti-ALS2CR8 antibody

ALS2CR8 may be a transcription factor (By similarity).

Product Categories/Family for anti-ALS2CR8 antibody

Antibodies; Disease Markers

References

Cheung, C.T., et al. Mech. Ageing Dev. 130 (1-2), 18-23 (2009): Hillier, L.W., et al. Nature 434(7034):724-731(2005). Hasan, M.K., et al. J. Biol. Chem. 277(40):37765-37770(2002). Tao, X., et al. Neuron 33(3):383-395(2002). Hadano, S., et al. Nat. Genet. 29(2):166-173(2001).

NCBI and Uniprot Product Information

• NCBI GI #: 157168372
• NCBI GeneID: 79800
• NCBI Accession #: NP_001098056.1
• NCBI GenBank Nucleotide #: NM_001104586.1
• UniProt Accession #: Q8N187; Q8ND29; Q8WXC0; Q96J78; Q96Q38; Q96Q39; Q9H712
• Molecular Weight: 80,698 Da
• NCBI Official Full Name: amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein
• NCBI Official Synonym Full Names: calcium responsive transcription factor
• NCBI Official Symbol: CARF
• NCBI Official Synonym Symbols: ALS2CR8; NYD-SP24
• NCBI Protein Information: amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein; calcium-response factor; testis development protein NYD-SP24; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 8
• UniProt Protein Name: Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein
• UniProt Gene Name: ALS2CR8
• UniProt Synonym Gene Names: CARF; CaRF
• UniProt Entry Name: AL2S8_HUMAN

Uniprot Description

CARF: May be a transcription factor. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 2q33.2

Cellular Component: nucleoplasm; nucleolus; nucleus

Molecular Function: DNA binding; transcription factor activity

Biological Process: transcription, DNA-dependent