Rabbit anti-Human, Mouse ALS2CR7 Polyclonal Antibody

ALS2CR7, NT (Cell Division Protein Kinase 15, Serine/Threonine-protein Kinase PFTAIRE-2, Serine/Threonine-protein Kinase ALS2CR7, Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene Protein 7, CDK15, PFTK2)

Cat. Num. AAA628471

• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity Purified; Purified by Protein G affinity chromatography.
• Synonyms: ALS2CR7; Polyclonal Antibody; NT (Cell Division Protein Kinase 15; Serine/Threonine-protein Kinase PFTAIRE-2; Serine/Threonine-protein Kinase ALS2CR7; Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene Protein 7; CDK15; PFTK2); Anti -ALS2CR7; anti-ALS2CR7 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human ALS2CR7. Species Crossreactivity: mouse.
• Purity/Purification: Affinity Purified; Purified by Protein G affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, 0.09% sodium azide.

• Applicable Applications for anti-ALS2CR7 antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in ELISA, Western Blot, and Immunohistochemistry.; Dilution: ELISA: 1:1,000; Western Blot: 1:100-1:500; Immunohistochemistry: 1:50-1:100
• Immunogen: Synthetic peptide selected from the N-terminal region of human ALS2CR7 (KLH).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(ALS2CR7 Antibody (R13) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the ALS2CR7 antibody detected the ALS2CR7 protein (arrow).)

Related Product Information for anti-ALS2CR7 antibody

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.

Product Categories/Family for anti-ALS2CR7 antibody

Antibodies; Abs to Protein Kinases

NCBI and Uniprot Product Information

• NCBI GI #: 15823642
• NCBI Official Full Name: ALS2CR7

Uniprot Description

CDK15: a CMGC kinase of the CDK family.

Protein type: Protein kinase, CMGC; Kinase, protein; Cell cycle regulation; EC 2.7.11.22; Protein kinase, Ser/Thr (non-receptor); CMGC group; CDK family; CDK/TAIRE subfamily; TAIRE subfamily

Chromosomal Location of Human Ortholog: 2q33.2

Molecular Function: protein serine/threonine kinase activity; protein binding; cyclin-dependent protein kinase activity; metal ion binding; ATP binding

Biological Process: regulation of cell cycle; protein amino acid phosphorylation