Rabbit Alpha T-catenin Polyclonal Antibody | anti-CTNNA3 antibody

Anti-Alpha T-catenin Antibody

Cat. Num. AAA8306389

• Gene Names: CTNNA3; VR22; ARVD13
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: Purified by Immunogen Affinity Chromatography
• Synonyms: Alpha T-catenin; Polyclonal Antibody; Anti-Alpha T-catenin Antibody; Catenin alpha-3; Cadherin-associated protein; anti-CTNNA3 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Specificity: Recognizes endogenous levels of Alpha T-catenin protein.
• Purity/Purification: Purified by Immunogen Affinity Chromatography
• Form/Format: Liquid in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3, 30% Glycerol, and 0.01% Sodium Azide.

• Applicable Applications for anti-CTNNA3 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:2000
• Immunogen: Recombinant fusion protein of human Alpha T-catenin. The exact sequence is proprietary.
• Preparation and Storage: Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of Alpha T-catenin expression in HEK293T (A), mouse spleen (B), rat brain (C) whole cell lysates.)

Related Product Information for anti-CTNNA3 antibody

Rabbit polyclonal antibody to Alpha T-catenin

NCBI and Uniprot Product Information

• NCBI GI #: 78099215
• NCBI GeneID: 29119
• UniProt Accession #: Q9UI47; Q65CL1
• Molecular Weight: 895
• NCBI Official Full Name: Catenin alpha-3
• NCBI Official Synonym Full Names: catenin (cadherin-associated protein), alpha 3
• NCBI Official Symbol: CTNNA3
• NCBI Official Synonym Symbols: VR22; ARVD13
• NCBI Protein Information: catenin alpha-3; CTNNA3; alpha-T-catenin; alpha-catenin-like protein
• UniProt Protein Name: Catenin alpha-3
• Protein Family: Catenin
• UniProt Gene Name: CTNNA3
• UniProt Entry Name: CTNA3_HUMAN

NCBI Description

This gene encodes a protein that belongs to the vinculin/alpha-catenin family. The encoded protein plays a role in cell-cell adhesion in muscle cells. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia, familial 13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

Uniprot Description

CTNNA3: May be involved in formation of stretch-resistant cell- cell adhesion complexes. Belongs to the vinculin/alpha-catenin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion

Chromosomal Location of Human Ortholog: 10q22.2

Cellular Component: cytoskeleton; lamellipodium; cytoplasm; fascia adherens

Molecular Function: actin filament binding; protein binding; cadherin binding

Biological Process: cell-cell adhesion

Disease: Arrhythmogenic Right Ventricular Dysplasia, Familial, 13