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Testing Data (Sample(30 ug of whole cell lysate)A: HeLa S3B: MOLT412% SDS PAGEPrimary antibody diluted at 1: 500)

Rabbit anti-Human alpha sarcomeric Actin Polyclonal Antibody | anti-ACTC1 antibody

alpha sarcomeric Actin antibody

Gene Names
ACTC1; ACTC; ASD5; CMD1R; CMH11; LVNC4
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Purified by antigen-affinity chromatography.
Synonyms
alpha sarcomeric Actin; Polyclonal Antibody; alpha sarcomeric Actin antibody; anti-ACTC1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Purified by antigen-affinity chromatography.
Form/Format
Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Sequence Length
377
Applicable Applications for anti-ACTC1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Western blotting: 1:500-1:3000
Immunohistochemistry: 1:100-1:250
Immunogen Type
Recombinant protein
Immunogen Description
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 99 and 364 of Human ACTC1
Target Name
alpha sarcomeric Actin
Preparation and Storage
Store at -20 degree C for long term preservation (recommended). Store at 4 degree C for short term use.

Testing Data

(Sample(30 ug of whole cell lysate)A: HeLa S3B: MOLT412% SDS PAGEPrimary antibody diluted at 1: 500)

Testing Data (Sample(30 ug of whole cell lysate)A: HeLa S3B: MOLT412% SDS PAGEPrimary antibody diluted at 1: 500)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Gastric CA, using alpha Actin (cardiac muscle) antibody at 1: 100 dilution.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Gastric CA, using alpha Actin (cardiac muscle) antibody at 1: 100 dilution.)
Related Product Information for anti-ACTC1 antibody
Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). [provided by RefSeq]
Product Categories/Family for anti-ACTC1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
70
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
42,019 Da
NCBI Official Full Name
actin, alpha cardiac muscle 1 proprotein
NCBI Official Synonym Full Names
actin, alpha, cardiac muscle 1
NCBI Official Symbol
ACTC1
NCBI Official Synonym Symbols
ACTC; ASD5; CMD1R; CMH11; LVNC4
NCBI Protein Information
actin, alpha cardiac muscle 1
UniProt Protein Name
Actin, alpha cardiac muscle 1
Protein Family
UniProt Gene Name
ACTC1
UniProt Synonym Gene Names
ACTC
UniProt Entry Name
ACTC_HUMAN

NCBI Description

Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). [provided by RefSeq, Jul 2008]

Uniprot Description

ACTC1: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Belongs to the actin family.

Protein type: Contractile; Cell development/differentiation; Cytoskeletal; Myosin-binding; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 15q14

Cellular Component: I band; extracellular space; sarcomere; focal adhesion; membrane; cytoplasm; actin filament; cytosol

Molecular Function: myosin binding; ATPase activity; ATP binding

Biological Process: response to drug; apoptosis; muscle thin filament assembly; actin filament-based movement; metabolic process; actomyosin structure organization and biogenesis; cardiac myofibril assembly; muscle filament sliding; response to ethanol; heart contraction; cardiac muscle morphogensis; actin-myosin filament sliding; negative regulation of apoptosis; cardiac muscle contraction

Disease: Atrial Septal Defect 5; Cardiomyopathy, Familial Hypertrophic, 11; Cardiomyopathy, Dilated, 1r

Research Articles on ACTC1

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Product Notes

The ACTC1 actc1 (Catalog #AAA9405955) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The alpha sarcomeric Actin antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's alpha sarcomeric Actin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western blotting: 1:500-1:3000 Immunohistochemistry: 1:100-1:250. Researchers should empirically determine the suitability of the ACTC1 actc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "alpha sarcomeric Actin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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