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Testing Data #1 (Native Human Alpha-1 Microglobulin detected with Sheep anti Human Alpha-1 Microglobulin:HRP (MBS223921))

Sheep ALPHA 1 MICROGLOBULIN Polyclonal Antibody | anti-AMBP antibody

SHEEP ANTI HUMAN ALPHA 1 MICROGLOBULIN

Gene Names
AMBP; A1M; HCP; ITI; UTI; EDC1; HI30; ITIL; IATIL; ITILC
Applications
ELISA, Immunodiffusion
Synonyms
ALPHA 1 MICROGLOBULIN; Polyclonal Antibody; SHEEP ANTI HUMAN ALPHA 1 MICROGLOBULIN; anti-AMBP antibody
Ordering
For Research Use Only!
Host
Sheep
Clonality
Polyclonal
Isotype
IgG
Form/Format
Purified
Purified IgG - liquid
Concentration
Approximate Protein Concentration: 5mg/ml (varies by lot)
Sequence Length
352
Applicable Applications for anti-AMBP antibody
ELISA (EIA), Immunodiffusion (ID)
Application Notes
ELISA: Minimum Dilution: 1/500; Maximum Dilution: 1/1000
Perservative Stabilisers
0.09% Sodium Azide (NaN3)>
Preparation
Immunogen
Highly pure human alpha-1-microglobulin, prepared from the urine of patients with chronic renal proteinuria (molecular weight 25-30 kD).
Buffer Solution
Antiserum Preparation
Antisera to human alpha-1-microglubulin were raised by repeated immunisations of sheep with highly purified antigen.
Target Species
Human
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted.
Shelf Life: 18 months from date of despatch.

Testing Data #1

(Native Human Alpha-1 Microglobulin detected with Sheep anti Human Alpha-1 Microglobulin:HRP (MBS223921))

Testing Data #1 (Native Human Alpha-1 Microglobulin detected with Sheep anti Human Alpha-1 Microglobulin:HRP (MBS223921))
Related Product Information for anti-AMBP antibody
Sheep anti Human alpha 1 microglobulin antibody recognizes human alpha 1 microglobulin. Sheep anti Human alpha 1 microglobulin antibody does not demonstrate any cross reactivity with urine albumin, retinol binding protein or beta-2 microglobulin in performed testing.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
259
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38,999 Da
NCBI Official Full Name
protein AMBP preproprotein
NCBI Official Synonym Full Names
alpha-1-microglobulin/bikunin precursor
NCBI Official Symbol
AMBP
NCBI Official Synonym Symbols
A1M; HCP; ITI; UTI; EDC1; HI30; ITIL; IATIL; ITILC
NCBI Protein Information
protein AMBP; bikunin; complex-forming glycoprotein heterogeneous in charge; growth-inhibiting protein 19; inter-alpha-trypsin inhibitor light chain; protein HC; trypstatin; uristatin; uronic-acid-rich protein
UniProt Protein Name
Protein AMBP
Protein Family
UniProt Gene Name
AMBP
UniProt Synonym Gene Names
HCP; ITIL; Protein HC; ITI-LC
UniProt Entry Name
AMBP_HUMAN

NCBI Description

This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes. [provided by RefSeq, Jul 2008]

Uniprot Description

AMBP: Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 9q32-q33

Cellular Component: extracellular space; cell surface; intracellular membrane-bound organelle; plasma membrane; extracellular region

Molecular Function: serine-type endopeptidase inhibitor activity; protein binding; protein homodimerization activity; calcium oxalate binding; heme binding; IgA binding; calcium channel inhibitor activity

Biological Process: receptor-mediated endocytosis; negative regulation of JNK cascade; viral reproduction; heme catabolic process; negative regulation of immune response; protein catabolic process; female pregnancy; cell adhesion; protein-chromophore linkage

Research Articles on AMBP

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Product Notes

The AMBP ambp (Catalog #AAA221001) is an Antibody produced from Sheep and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's ALPHA 1 MICROGLOBULIN can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunodiffusion (ID). ELISA: Minimum Dilution: 1/500; Maximum Dilution: 1/1000. Researchers should empirically determine the suitability of the AMBP ambp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ALPHA 1 MICROGLOBULIN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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