Western Blot (WB)
(ALG10B Antibody (C-term) western blot analysis in A549 cell line lysates (15ug/lane).This demonstrates the ALG10B antibody detected the ALG10B protein (arrow).)
Rabbit anti-Human ALG10B Polyclonal Antibody | anti-ALG10B antibody
ALG10B Antibody (C-term)
Gene Names
ALG10B; KCR1; ALG10
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
ALG10B; Polyclonal Antibody; ALG10B Antibody (C-term); Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1; 2-glucosyltransferase; Alpha-1; 2-glucosyltransferase ALG10-A; Alpha-2-glucosyltransferase ALG10-B; Asparagine-linked glycosylation protein 10 homolog B; Potassium channel regulator 1; KCR1; anti-ALG10B antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This ALG10B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 324-353 amino acids from the C-terminal region of human ALG10B.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
324-353
Sequence Length
473
Applicable Applications for anti-ALG10B antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(ALG10B Antibody (C-term) western blot analysis in A549 cell line lysates (15ug/lane).This demonstrates the ALG10B antibody detected the ALG10B protein (arrow).)
Western Blot (WB)
(ALG10B Antibody (C-term) western blot analysis in A549 cell line lysates (15ug/lane).This demonstrates the ALG10B antibody detected the ALG10B protein (arrow).)
Related Product Information for anti-ALG10B antibody
Putative alpha-1,2-glucosyltransferase, which adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol. When coupled to KCNH2 may reduce KCNH2 sensitivity to classic proarrhythmic drug blockade, possibly by mediating glycosylation of KCNH2.
Product Categories/Family for anti-ALG10B antibody
References
Daly, A.K., et al. Nat. Genet. 41(7):816-819(2009)
Petersen, C.I., et al. Proc. Natl. Acad. Sci. U.S.A. 101(32):11773-11778(2004)
Kupershmidt, S., et al. FASEB J. 17(15):2263-2265(2003)
Petersen, C.I., et al. Proc. Natl. Acad. Sci. U.S.A. 101(32):11773-11778(2004)
Kupershmidt, S., et al. FASEB J. 17(15):2263-2265(2003)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
55448
NCBI Official Full Name
putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase isoform 1
NCBI Official Synonym Full Names
ALG10B, alpha-1,2-glucosyltransferase
NCBI Official Symbol
ALG10B
NCBI Official Synonym Symbols
KCR1; ALG10
NCBI Protein Information
putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase
UniProt Protein Name
Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase
UniProt Gene Name
ALG10B
UniProt Synonym Gene Names
KCR1
UniProt Entry Name
AG10B_HUMAN
Uniprot Description
ALG10B: Putative alpha-1,2-glucosyltransferase, which adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol. When coupled to KCNH2 may reduce KCNH2 sensitivity to classic proarrhythmic drug blockade, possibly by mediating glycosylation of KCNH2. Belongs to the ALG10 glucosyltransferase family.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transferase; EC 2.4.1.256; Glycan Metabolism - N-glycan biosynthesis
Chromosomal Location of Human Ortholog: 12q12
Cellular Component: integral to membrane; plasma membrane
Molecular Function: transferase activity, transferring hexosyl groups
Biological Process: cellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; protein amino acid N-linked glycosylation via asparagine; post-translational protein modification
Research Articles on ALG10B
Similar Products
Product Notes
The ALG10B alg10b (Catalog #AAA9206332) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 324-353. The ALG10B Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ALG10B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the ALG10B alg10b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ALG10B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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