Western Blot (WB)
(ALDH8A1 Antibody (C-term) western blot analysis in mouse liver tissue lysates (15ug/lane).This demonstrates the ALDH8A1 antibody detected ALDH8A1 protein (arrow).)
Rabbit anti-Human ALDH8A1 Polyclonal Antibody | anti-ALDH8A1 antibody
ALDH8A1, CT (Aldehyde Dehydrogenase Family 8 Member A1, Aldehyde Dehydrogenase 12, ALDH12) (Azide free) (HRP)
ELISA: 1:1,000
WB: 1:50-1:100
Applications are based on unconjugated antibody.
Western Blot (WB)
(ALDH8A1 Antibody (C-term) western blot analysis in mouse liver tissue lysates (15ug/lane).This demonstrates the ALDH8A1 antibody detected ALDH8A1 protein (arrow).)
Western Blot (WB)
(ALDH8A1 Antibody (C-term) western blot analysis in mouse liver tissue lysates (15ug/lane).This demonstrates the ALDH8A1 antibody detected ALDH8A1 protein (arrow).)
Western Blot (WB)
(ALDH8A1 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ALDH8A1 antibody detected the ALDH8A1 protein (arrow).)
Western Blot (WB)
(ALDH8A1 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ALDH8A1 antibody detected the ALDH8A1 protein (arrow).)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the aldehyde dehydrogenase family of proteins. The encoded protein has been implicated in the synthesis of 9-cis-retinoic acid and in the breakdown of the amino acid tryptophan. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. In addition, this enzyme has been shown to catalyze the conversion of 2-aminomuconic semialdehyde to 2-aminomuconate in the kynurenine pathway of tryptophan catabolism. [provided by RefSeq, Jul 2018]
Uniprot Description
ALDH8A1: Converts 9-cis-retinal to 9-cis-retinoic acid. Has lower activity towards 13-cis-retinal. Has much lower activity towards all-trans-retinal. Has highest activity with benzaldehyde and decanal (in vitro). Has a preference for NAD, but shows considerable activity with NADP (in vitro). Belongs to the aldehyde dehydrogenase family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 1.2.1.-; Oxidoreductase
Chromosomal Location of Human Ortholog: 6q23.2
Cellular Component: cytoplasm; intracellular
Molecular Function: aldehyde dehydrogenase (NAD) activity; retinal dehydrogenase activity
Biological Process: retinal metabolic process; 9-cis-retinoic acid biosynthetic process; retinoic acid metabolic process
Research Articles on ALDH8A1
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Product Notes
The ALDH8A1 aldh8a1 (Catalog #AAA6462373) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ALDH8A1, CT (Aldehyde Dehydrogenase Family 8 Member A1, Aldehyde Dehydrogenase 12, ALDH12) (Azide free) (HRP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ALDH8A1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB). IHC: 1:10-1:50 ELISA: 1:1,000 WB: 1:50-1:100 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the ALDH8A1 aldh8a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ALDH8A1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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