Western Blot (WB)
(Western Blot analysis of ALDH3B1 in Human normal kidney and liver tissue, human liver cancer tissue in order using ALDH3B1 Rabbit pAb at dilution 1/200)
Rabbit ALDH3B1 Polyclonal Antibody | anti-ALDH3B1 antibody
ALDH3B1 Rabbit pAb
IHC-P: 1:25-1:100
Western Blot (WB)
(Western Blot analysis of ALDH3B1 in Human normal kidney and liver tissue, human liver cancer tissue in order using ALDH3B1 Rabbit pAb at dilution 1/200)
Western Blot (WB)
(Western Blot analysis of ALDH3B1 in Human normal kidney and liver tissue, human liver cancer tissue in order using ALDH3B1 Rabbit pAb at dilution 1/200)
Immunohistochemistry (IHC)
(Immunohistochemistry of ALDH3B1 in paraffin-embedded Human thyroid cancer tissue using ALDH3B1 Rabbit pAb at dilution 1/20. Predicted cell location: Cytoplasm)
Immunohistochemistry (IHC)
(Immunohistochemistry of ALDH3B1 in paraffin-embedded Human thyroid cancer tissue using ALDH3B1 Rabbit pAb at dilution 1/20. Predicted cell location: Cytoplasm)
NCBI and Uniprot Product Information
NCBI Description
The aldehyde dehydrogenases are a family of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular gene spans about 20 kb of genomic DNA and is composed of 9 coding exons. The gene is highly expressed in kidney and lung. The functional significance of this gene as well as the cellular localization of its product are presently unknown. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]
Uniprot Description
ALDH3B1: Oxidizes medium and long chain saturated and unsaturated aldehydes. Metabolizes also benzaldehyde. Low activity towards acetaldehyde and 3,4-dihydroxyphenylacetaldehyde. May not metabolize short chain aldehydes. May use both NADP(+) and NAD(+) as cofactors. May have a protective role against the cytotoxicity induced by lipid peroxidation. Belongs to the aldehyde dehydrogenase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Amino Acid Metabolism - tyrosine; Carbohydrate Metabolism - glycolysis and gluconeogenesis; EC 1.2.1.5; Oxidoreductase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - metabolism by cytochrome P450; Amino Acid Metabolism - histidine; Amino Acid Metabolism - phenylalanine
Chromosomal Location of Human Ortholog: 11q13
Cellular Component: cytoplasm; plasma membrane; cytosol; vesicle
Molecular Function: aldehyde dehydrogenase [NAD(P)+] activity; 3-chloroallyl aldehyde dehydrogenase activity
Biological Process: aldehyde catabolic process; ethanol catabolic process; alcohol metabolic process; lipid metabolic process
Research Articles on ALDH3B1
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Product Notes
The ALDH3B1 aldh3b1 (Catalog #AAA4758859) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ALDH3B1 Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ALDH3B1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:200-1:1000 IHC-P: 1:25-1:100. Researchers should empirically determine the suitability of the ALDH3B1 aldh3b1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ALDH3B1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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