Rabbit anti-Rat ALDH1A1 Polyclonal Antibody | anti-ALDH1A1 antibody
ALDH1A1 Antibody BIOTIN-Conjugated
Immunoprecipitation: 1:200
Western Blot: 1:2,500-1:5,000
Is capable of converting 9-cis and all-trans retinal to corresponding retinoic acid with high efficiency, 9-cis retinal being 2-fold more active than all-trans retinal.
NCBI and Uniprot Product Information
NCBI Description
ubiquitous enzyme located in virtually all mammalian tissues; catalyzes oxidation of aldehyde substrates to carboxylic acids; detoxifies ethanol-derived acetaldehyde [RGD, Feb 2006]
Uniprot Description
ALDH1A1: Binds free retinal and cellular retinol-binding protein- bound retinal. Can convert/oxidize retinaldehyde to retinoic acid. Belongs to the aldehyde dehydrogenase family.
Protein type: GAPs, Ras; Apoptosis; EC 1.2.1.36; GAPs; Oxidoreductase; Cofactor and Vitamin Metabolism - retinol
Cellular Component: cytoplasm; nucleus
Molecular Function: 3-chloroallyl aldehyde dehydrogenase activity; aldehyde dehydrogenase (NAD) activity; benzaldehyde dehydrogenase (NAD+) activity; identical protein binding; retinal dehydrogenase activity
Biological Process: 9-cis-retinoic acid biosynthetic process; 9-cis-retinoic acid metabolic process; embryonic eye morphogenesis; kidney development; liver development; midgut development; optic cup morphogenesis involved in camera-type eye development; positive regulation of apoptosis; protein homotetramerization; response to drug; response to estradiol stimulus; response to ethanol; response to organic cyclic substance; response to oxidative stress; response to retinoic acid; retinoic acid metabolic process; retinol metabolic process
Research Articles on ALDH1A1
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Product Notes
The ALDH1A1 aldh1a1 (Catalog #AAA540960) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ALDH1A1 Antibody BIOTIN-Conjugated reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ALDH1A1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB). ELISA: 1:50,000 Immunoprecipitation: 1:200 Western Blot: 1:2,500-1:5,000. Researchers should empirically determine the suitability of the ALDH1A1 aldh1a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ALDH1A1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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