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Western Blot (WB) (AKR1E2 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the AKR1E2 antibody detected the AKR1E2 protein (arrow).)

Rabbit AKR1E2 Polyclonal Antibody | anti-AKR1E2 antibody

AKR1E2 Antibody (C-term)

Gene Names
AKR1E2; hTSP; htAKR; AKRDC1; AKR1CL2; LoopADR
Reactivity
Human (Predicted Reactivity: Monkey)
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
AKR1E2; Polyclonal Antibody; AKR1E2 Antibody (C-term); 5-anhydro-D-fructose reductase; AF reductase; Aldo-keto reductase family 1 member C-like protein 2; Aldo-keto reductase family 1 member E2; LoopADR; Testis-specific protein; hTSP; AKR1CL2; AKRDC1; anti-AKR1E2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Monkey)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This AKR1E2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-320 amino acids from the C-terminal region of human AKR1E2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
291-320
Sequence Length
320
Applicable Applications for anti-AKR1E2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(AKR1E2 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the AKR1E2 antibody detected the AKR1E2 protein (arrow).)

Western Blot (WB) (AKR1E2 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the AKR1E2 antibody detected the AKR1E2 protein (arrow).)
Related Product Information for anti-AKR1E2 antibody
AKR1E2 catalyzes the NADPH-dependent reduction of 1,5-anhydro-D-fructose (AF) to 1,5-anhydro-D-glucitol. Can also catalyze the reduction of various aldehydes and quinones (By similarity). Has low NADPH-dependent reductase activity towards 9,10-phenanthrenequinone (in vitro).
Product Categories/Family for anti-AKR1E2 antibody
References
Clancy, R.M., et al. Arthritis Rheum. 62(11):3415-3424(2010)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Azuma, Y., et al. Mol. Hum. Reprod. 10(7):527-533(2004)
Nishinaka, T., et al. Chem. Biol. Interact. 143-144, 299-305 (2003) :

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
36589
NCBI Official Full Name
1,5-anhydro-D-fructose reductase isoform 1
NCBI Official Synonym Full Names
aldo-keto reductase family 1, member E2
NCBI Official Symbol
AKR1E2
NCBI Official Synonym Symbols
hTSP; htAKR; AKRDC1; AKR1CL2; LoopADR
NCBI Protein Information
1,5-anhydro-D-fructose reductase
UniProt Protein Name
1,5-anhydro-D-fructose reductase
UniProt Gene Name
AKR1E2
UniProt Synonym Gene Names
AKR1CL2; AKRDC1; AF reductase; hTSP
UniProt Entry Name
AKCL2_HUMAN

NCBI Description

The protein encoded by this gene is a member of the aldo-keto reductase superfamily. Members in this family are characterized by their structure (evolutionarily highly conserved TIM barrel) and function (NAD(P)H-dependent oxido-reduction of carbonyl groups). Transcripts of this gene have been reported in specimens of human testis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Uniprot Description

AKR1CL2: Catalyzes the NADPH-dependent reduction of 1,5-anhydro- D-fructose (AF) to 1,5-anhydro-D-glucitol. Can also catalyze the reduction of various aldehydes and quinones. Has low NADPH-dependent reductase activity towards 9,10- phenanthrenequinone (in vitro). Belongs to the aldo/keto reductase family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Oxidoreductase; EC 1.1.1.263

Chromosomal Location of Human Ortholog: 10p15.1

Cellular Component: cytoplasm

Molecular Function: 1,5-anhydro-D-fructose reductase activity

Research Articles on AKR1E2

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Product Notes

The AKR1E2 akr1e2 (Catalog #AAA9211389) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 291-320. The AKR1E2 Antibody (C-term) reacts with Human (Predicted Reactivity: Monkey) and may cross-react with other species as described in the data sheet. AAA Biotech's AKR1E2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the AKR1E2 akr1e2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AKR1E2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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