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Western Blot (WB) (Western Blot analysis of Rat liver, Rat lung tissue and Jurkat cells using AIMP2 Polyclonal Antibody at dilution of 1:600)

Rabbit anti-Human, Rat AIMP2 Polyclonal Antibody | anti-AIMP2 antibody

AIMP2 Polyclonal Antibody

Gene Names
AIMP2; P38; JTV1; JTV-1
Reactivity
Human, Rat
Applications
Western Blot
Purity
Antigen Affinity Purification
Synonyms
AIMP2; Polyclonal Antibody; AIMP2 Polyclonal Antibody; Aminoacyl tRNA synthetase complex interacting multifunctional protein 2; ARS interacting multi functional protein 2; P38; Protein JTV 1; anti-AIMP2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Concentration
4mg/ml (varies by lot)
Sequence Length
320
Applicable Applications for anti-AIMP2 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
Recombinant Human Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 protein
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western Blot analysis of Rat liver, Rat lung tissue and Jurkat cells using AIMP2 Polyclonal Antibody at dilution of 1:600)

Western Blot (WB) (Western Blot analysis of Rat liver, Rat lung tissue and Jurkat cells using AIMP2 Polyclonal Antibody at dilution of 1:600)
Related Product Information for anti-AIMP2 antibody
Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
Product Categories/Family for anti-AIMP2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Calculated MW: 35kD
Observed MW: 35kD
NCBI Official Full Name
aminoacyl tRNA synthase complex-interacting multifunctional protein 2 isoform a
NCBI Official Synonym Full Names
aminoacyl tRNA synthetase complex interacting multifunctional protein 2
NCBI Official Symbol
AIMP2
NCBI Official Synonym Symbols
P38; JTV1; JTV-1
NCBI Protein Information
aminoacyl tRNA synthase complex-interacting multifunctional protein 2
UniProt Protein Name
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2
UniProt Gene Name
AIMP2
UniProt Synonym Gene Names
JTV1
UniProt Entry Name
AIMP2_HUMAN

NCBI Description

The protein encoded by this gene is part of the aminoacyl-tRNA synthetase complex, which contains nine different aminoacyl-tRNA synthetases and three non-enzymatic factors. The encoded protein is one of the non-enzymatic factors and is required for assembly and stability of the complex. [provided by RefSeq, May 2016]

Uniprot Description

JTV1: Required for assembly and stability of the aminoacyl- tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down- regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.

Chromosomal Location of Human Ortholog: 7p22

Cellular Component: cytosol; membrane

Molecular Function: protein binding

Biological Process: tRNA aminoacylation for protein translation

Research Articles on AIMP2

Similar Products

Product Notes

The AIMP2 aimp2 (Catalog #AAA2541741) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AIMP2 Polyclonal Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's AIMP2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the AIMP2 aimp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AIMP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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