Testing Data
Mouse VGlut1 Monoclonal Antibody | anti-SLC17A7 antibody
VGlut1 Transporter Monoclonal Antibody
Immunohistochemistry: Use at 1-5ug/ml.
Testing Data
Testing Data
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a vesicle-bound, sodium-dependent phosphate transporter that is specifically expressed in the neuron-rich regions of the brain. It is preferentially associated with the membranes of synaptic vesicles and functions in glutamate transport. The protein shares 82% identity with the differentiation-associated Na-dependent inorganic phosphate cotransporter and they appear to form a distinct class within the Na+/Pi cotransporter family. [provided by RefSeq, Jul 2008]
Uniprot Description
SLC17A7: Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.
Protein type: Transporter, SLC family; Membrane protein, integral; Vesicle; Membrane protein, multi-pass; Transporter
Chromosomal Location of Human Ortholog: 19q13
Cellular Component: cell junction; excitatory synapse; integral to membrane; plasma membrane; presynaptic active zone; synaptic vesicle membrane
Molecular Function: extracellular-glutamate-gated chloride channel activity; inorganic phosphate transmembrane transporter activity; L-glutamate transmembrane transporter activity; sodium-dependent phosphate transmembrane transporter activity; sodium:inorganic phosphate symporter activity
Biological Process: brain development; glutamate secretion; ion transport; L-glutamate import; long-term memory; neurotransmitter transport; phosphate transport; regulation of excitatory postsynaptic membrane potential; sequestering of neurotransmitter; synaptic transmission, glutamatergic
Research Articles on SLC17A7
Similar Products
Product Notes
The SLC17A7 slc17a7 (Catalog #AAA190898) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's VGlut1 can be used in a range of immunoassay formats including, but not limited to, Immunoblot (IB), Immunohistochemistry (IHC). Immunoblotting: Use at 1-2ug/ml. A band of ~52kDa is detected. Immunohistochemistry: Use at 1-5ug/ml. Researchers should empirically determine the suitability of the SLC17A7 slc17a7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VGlut1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
