Western Blot (WB)
(Western Blot analysis of extracts of various cell lines, using AHCYL1 antibody.)
Rabbit AHCYL1 Polyclonal Antibody | anti-AHCYL1 antibody
AHCYL1 Polyclonal Antibody
Gene Names
AHCYL1; DCAL; IRBIT; PPP1R78; PRO0233; XPVKONA
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
AHCYL1; Polyclonal Antibody; AHCYL1 Polyclonal Antibody; DCAL; IRBIT; XPVKONA; Adenosylhomocysteinase 2; AdoHcyase 2; anti-AHCYL1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
AHCYL1 polyclonal antibody detects endogenous levels of AHCYL1 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
483
Applicable Applications for anti-AHCYL1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
IHC: 1:50-1:200
Immunogen
Recombinant protein of human AHCYL1.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot analysis of extracts of various cell lines, using AHCYL1 antibody.)
Western Blot (WB)
(Western Blot analysis of extracts of various cell lines, using AHCYL1 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human stomach using AHCYL1 antibody at dilution of 1:100 (x40 lens).)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human stomach using AHCYL1 antibody at dilution of 1:100 (x40 lens).)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded rat kidney using AHCYL1 antibody at dilution of 1:100 (x40 lens).)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded rat kidney using AHCYL1 antibody at dilution of 1:100 (x40 lens).)
Related Product Information for anti-AHCYL1 antibody
AHCYL1 (S-adenosylhomocysteine hydrolase-like 1), also known as DCAL, IRBIT or PRO0233, is an endoplasmic reticulum (ER) protein that is involved in amino acid biosynthesis. Expressed in dentritic blood cells (DCs), AHCYL1 functions to catalyze the H(2)O-dependent conversion of S-adenosyl-L-homocysteine to L-homocysteine and adenosine, a reaction that uses NAD as a cofactor. Additionally, AHCYL1 contains a PDZ-binding domain and a PEST region through which it can interact with IP3R-I (inositol 1, 4, 5-trisphosphate (IP3) receptor-I), a protein involved in various signaling pathways. This interaction lowers the affinity of IP3R-1 for its substrate, IP3, thereby decreasing the rate of IP3-IP3R-I binding. AHCYL1 shares 100% homology with its mouse counterpart, indicating a highly conserved function between species. Two isoforms of AHCYL1 are expressed due to alternative splicing events.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 59kDa
NCBI Official Full Name
S-adenosylhomocysteine hydrolase-like protein 1 isoform b
NCBI Official Synonym Full Names
adenosylhomocysteinase like 1
NCBI Official Symbol
AHCYL1
NCBI Official Synonym Symbols
DCAL; IRBIT; PPP1R78; PRO0233; XPVKONA
NCBI Protein Information
S-adenosylhomocysteine hydrolase-like protein 1
UniProt Protein Name
Putative adenosylhomocysteinase 2
Protein Family
UniProt Gene Name
AHCYL1
UniProt Synonym Gene Names
DCAL; XPVKONA; AdoHcyase 2; IRBIT
UniProt Entry Name
SAHH2_HUMAN
NCBI Description
The protein encoded by this gene interacts with inositol 1,4,5-trisphosphate receptor, type 1 and may be involved in the conversion of S-adenosyl-L-homocysteine to L-homocysteine and adenosine. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Research Articles on AHCYL1
Similar Products
Product Notes
The AHCYL1 ahcyl1 (Catalog #AAA3009414) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AHCYL1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's AHCYL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:2000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the AHCYL1 ahcyl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AHCYL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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