Rabbit anti-Human AGTRAP Polyclonal Antibody | anti-AGTRAP antibody

AGTRAP, CT (AGTRAP, ATRAP, Type-1 angiotensin II receptor-associated protein, AT1 receptor-associated protein) (FITC)

Cat. Num. AAA6272325

• Gene Names: AGTRAP; ATRAP
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: AGTRAP; Polyclonal Antibody; CT (AGTRAP; ATRAP; Type-1 angiotensin II receptor-associated protein; AT1 receptor-associated protein) (FITC); AT1 receptor-associated protein; anti-AGTRAP antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human AGTRAP.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-AGTRAP antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: AGTRAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-159 amino acids from the C-terminal region of human AGTRAP.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(AGTRAP Antibody (C-term) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the AGTRAP Antibody detected the AGTRAP protein (arrow).)

Related Product Information for anti-AGTRAP antibody

This gene encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. The gene product interacts with the angiotensin II type I receptor and negatively regulates angiotensin II signaling. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms.

Product Categories/Family for anti-AGTRAP antibody

Antibodies; Angiotensin(ogen)

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010). Godin, C.M., et al. Mol. Pharmacol. 77(3):388-395(2010). Rabbitts, J.A., et al. J. Physiol. (Lond.) 587 (PT 22), 5441-5449 (2009): Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009). Newton-Cheh, C., et al. Nat. Genet. 41(6):666-676(2009).

NCBI and Uniprot Product Information

• NCBI GI #: 93588491
• NCBI GeneID: 57085
• NCBI Accession #: NP_001035284.1
• NCBI GenBank Nucleotide #: NM_001040194.1
• UniProt Accession #: Q6RW13; Q5SNV4; Q5SNV5; Q96AC0; Q96PL4; Q9NRW9; A8MVQ5
• Molecular Weight: 17,419 Da
• NCBI Official Full Name: type-1 angiotensin II receptor-associated protein isoform b
• NCBI Official Synonym Full Names: angiotensin II receptor-associated protein
• NCBI Official Symbol: AGTRAP
• NCBI Official Synonym Symbols: ATRAP
• NCBI Protein Information: type-1 angiotensin II receptor-associated protein; AT1 receptor-associated protein; ATI receptor-associated protein; angiotensin II, type I receptor-associated protein
• UniProt Protein Name: Type-1 angiotensin II receptor-associated protein
• Protein Family: Type-1 angiotensin II receptor-associated protein
• UniProt Gene Name: AGTRAP
• UniProt Synonym Gene Names: ATRAP
• UniProt Entry Name: ATRAP_HUMAN