Rabbit anti-Human AGTRAP Polyclonal Antibody | anti-AGTRAP antibody
AGTRAP Antibody
Reactivity
Human
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
AGTRAP; Polyclonal Antibody; AGTRAP Antibody; Agtrap; Angiotensin II receptor associated protein; Angiotensin II type I receptor associated protein; AT1 receptor-associated protein; ATI receptor associated protein; ATRAP; ATRAP_HUMAN; MGC29646; OTTHUMP00000002269; OTTHUMP00000002270; OTTHUMP00000002271; Type 1 angiotensin II receptor associated protein; Type-1 angiotensin II receptor-associated protein; anti-AGTRAP antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
AGTRAP Antibody detects endogenous levels of AGTRAP.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-AGTRAP antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human AGTRAP.
Conjugation
Unconjugated
Subunit Structure
Interacts with RACK1, and with the C-terminal region of AGTR1.
Tissue Specificity
Ubiquitous but more abundant in kidney, heart, pancreas and thyroid.
Function
Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity.
Note
Present in perinuclear vesicular membranes, Endoplasmic reticulum, Golgi and endocytic vesicles.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-AGTRAP antibody
NCBI and Uniprot Product Information
NCBI GeneID
UniProt Accession #
Molecular Weight
Predicted Mol.Wt.: 17kDa(Calculated)
UniProt Protein Name
Type-1 angiotensin II receptor-associated protein
Protein Family
UniProt Gene Name
AGTRAP
UniProt Synonym Gene Names
ATRAP
UniProt Entry Name
ATRAP_HUMAN
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Product Notes
The AGTRAP agtrap (Catalog #AAA9631196) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AGTRAP Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's AGTRAP can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the AGTRAP agtrap for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AGTRAP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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