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Testing Data (Gel: 10%SDS-PAGE Lysate: 40 ug Mouse Large intestine tissue lysate Primary antibody: 1/1000 dilution Secondary antibody: Donkey anti Rabbit IgG - H&L (HRP) at 1/3000 dilution Exposure time: 20 seconds)

Rabbit anti-Human, Mouse AGR2 Polyclonal Antibody | anti-AGR2 antibody

AGR2 Antibody

Gene Names
AGR2; AG2; GOB-4; HAG-2; XAG-2; PDIA17; HEL-S-116
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Synonyms
AGR2; Polyclonal Antibody; AGR2 Antibody; Anterior gradient protein 2 homolog; AG2; GOB-4; HAG-2; XAG-2; PDIA17; anti-AGR2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total AGR2 protein.
Form/Format
Supplied at 0.7mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.
Sequence Length
836
Applicable Applications for anti-AGR2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:1000-1:10000
Western blotting: 1:1000-1:5000
Immunohistochemistry: 1:10-1:50
Immunogen Type
Recombinant Protein
Immunogen Description
Full length fusion protein
Target Name
AGR2
Preparation and Storage
Store at -20 degree C/1 year

Testing Data

(Gel: 10%SDS-PAGE Lysate: 40 ug Mouse Large intestine tissue lysate Primary antibody: 1/1000 dilution Secondary antibody: Donkey anti Rabbit IgG - H&L (HRP) at 1/3000 dilution Exposure time: 20 seconds)

Testing Data (Gel: 10%SDS-PAGE Lysate: 40 ug Mouse Large intestine tissue lysate Primary antibody: 1/1000 dilution Secondary antibody: Donkey anti Rabbit IgG - H&L (HRP) at 1/3000 dilution Exposure time: 20 seconds)

Immunohistochemistry (IHC)

(The image on the left is immunohistochemistry of paraffin-embedded Human renal cancer tissue using 31005 (AGR2 Antibody) at dilution 1/10, on the right is treated with the fusion protein.)

Immunohistochemistry (IHC) (The image on the left is immunohistochemistry of paraffin-embedded Human renal cancer tissue using 31005 (AGR2 Antibody) at dilution 1/10, on the right is treated with the fusion protein.)
Related Product Information for anti-AGR2 antibody
Anterior gradient protein 2 homolog (AGR2) is a human protein originally discovered in Xenopus laevis, encoded for by the gene of the same name.In Xenopus AGR2 is an important role in cement gland differentiation, however in human cancer cell lines high levels of AGR2 correlate with reduction of the p53 response and AGR2 levels are elevated in the preneoplastic tissue Barrett's oesophagus.
Product Categories/Family for anti-AGR2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
19,979 Da
NCBI Official Full Name
Homo sapiens anterior gradient homolog 2 (Xenopus laevis), mRNA
NCBI Official Synonym Full Names
anterior gradient 2, protein disulphide isomerase family member
NCBI Official Symbol
AGR2
NCBI Official Synonym Symbols
AG2; GOB-4; HAG-2; XAG-2; PDIA17; HEL-S-116
NCBI Protein Information
anterior gradient protein 2 homolog
UniProt Protein Name
Anterior gradient protein 2 homolog
Protein Family
UniProt Gene Name
AGR2
UniProt Synonym Gene Names
AG2; AG-2; hAG-2
UniProt Entry Name
AGR2_HUMAN

Uniprot Description

AGR2: Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells. Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth. Interacts with LYPD3 and DAG1 (alphaDAG1). Interacts with MUC2; disulfide-linked. Expressed strongly in trachea, lung, stomach, colon, prostate and small intestine. Expressed weakly in pituitary gland, salivary gland, mammary gland, bladder, appendix, ovary, fetal lung, uterus, pancreas, kidney, fetal kidney, testis, placenta, thyroid gland and in estrogen receptor (ER)-positive breast cancer cell lines. Belongs to the AGR family.

Protein type: Secreted; Secreted, signal peptide; Oncoprotein

Chromosomal Location of Human Ortholog: 7p21.3

Cellular Component: mitochondrion; endoplasmic reticulum; extracellular region

Molecular Function: protein binding

Research Articles on AGR2

Similar Products

Product Notes

The AGR2 agr2 (Catalog #AAA9411547) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AGR2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's AGR2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:1000-1:10000 Western blotting: 1:1000-1:5000 Immunohistochemistry: 1:10-1:50. Researchers should empirically determine the suitability of the AGR2 agr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AGR2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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