Western Blot (WB)
(WB Suggested Anti-AGBL5 Antibody Titration: 0.2-1 ug/mlPositive Control: 721_B cell lysate)
Rabbit AGBL5 Polyclonal Antibody | anti-AGBL5 antibody
AGBL5 antibody - C-terminal region
Western Blot (WB)
(WB Suggested Anti-AGBL5 Antibody Titration: 0.2-1 ug/mlPositive Control: 721_B cell lysate)
Western Blot (WB)
(WB Suggested Anti-AGBL5 Antibody Titration: 0.2-1 ug/mlPositive Control: 721_B cell lysate)
Target Description: AGBL5 belongs to the peptidase M14 family. The exact function of AGBL5 remains unknown.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a metallocarboxypeptidase involved in protein deglutamylation and a member of the peptidase M14 family of proteins. The encoded protein has been described as a "dual-functional" deglutamylase that can remove glutamate residues from both carboxyl termini and side chains of protein substrates. This deglutamylase activity may be important in antiviral immunity. Mutations in this gene are associated with retinitis pigmentosa. [provided by RefSeq, Jul 2016]
Uniprot Description
Function: Metallocarboxypeptidase that mediates tubulin deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post-translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains, a process catalyzed by AGTPBP1/ CCP1, AGBL1/CCP4 and AGBL4/CCP6
By similarity.
Cofactor: Binds 1 zinc ion per subunit
By similarity.
Subcellular location: Cytoplasm › cytosol
By similarity. Nucleus
By similarity. Note: Mainly cytoplasmic. Slight accumulation in the nucleus is observed
By similarity.
Tissue specificity: Expressed in brain.
Sequence similarities: Belongs to the peptidase M14 family.
Sequence caution: The sequence AAX93164.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence AAY14655.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence BAB15151.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
Research Articles on AGBL5
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Product Notes
The AGBL5 agbl5 (Catalog #AAA3211492) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AGBL5 antibody - C-terminal region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's AGBL5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the AGBL5 agbl5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: RGLSSTLNVG VNKKRGLRTP PKSHNGLPVS CSENTLSRAR SFSTGTSAGG. It is sometimes possible for the material contained within the vial of "AGBL5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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