Rabbit AGAP1 Polyclonal Antibody | anti-AGAP1 antibody

AGAP1 Polyclonal Antibody

Cat. Num. AAA2523197

• Gene Names: AGAP1; GGAP1; AGAP-1; CENTG2; cnt-g2
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Antigen affinity purification
• Synonyms: AGAP1; Polyclonal Antibody; AGAP1 Polyclonal Antibody; GGAP1; AGAP-1; CENTG2; cnt-g2; anti-AGAP1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen affinity purification
• Concentration: 0.8mg/mL (varies by lot)
• Sequence Length: 405

• Applicable Applications for anti-AGAP1 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: WB: 1:500-1:2000; IHC: 1:25-1:100
• Immunogen: Synthetic peptide of human AGAP1
• Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3
• Preparation and Storage: Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Western Blot (WB)

(Western Blot analysis of Human liver cancer tissue, hela cell and Mouse lung tissue using AGAP1 Polyclonal Antibody at dilution of 1:400)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human thyroid cancer using AGAP1 Polyclonal Antibody at dilution of 1:25)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human liver cancer using AGAP1 Polyclonal Antibody at dilution of 1:25)

Related Product Information for anti-AGAP1 antibody

This gene encodes a member of an ADP-ribosylation factor GTPase-activating protein family involved in membrane trafficking and cytoskeleton dynamics. This gene functions as a direct regulator of the adaptor-related protein complex 3 on endosomes. Multiple transcript variants encoding different isoforms have been found for this gene. GTPase-activating protein for ARF1 and, to a lesser extent, ARF5. Directly and specifically regulates the adapter protein 3 (AP-3)-dependent trafficking of proteins in the endosomal-lysosomal system.

NCBI and Uniprot Product Information

• NCBI GI #: 349585207
• NCBI GeneID: 116987
• NCBI Accession #: NP_001231817.1
• NCBI GenBank Nucleotide #: NM_001244888.1
• Molecular Weight: 44,512 Da
• NCBI Official Full Name: arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform 3
• NCBI Official Synonym Full Names: ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
• NCBI Official Symbol: AGAP1
• NCBI Official Synonym Symbols: GGAP1; AGAP-1; CENTG2; cnt-g2
• NCBI Protein Information: arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1; Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 1; GTP-binding and GTPase-activating protein 1; centaurin, gamma 2
• UniProt Protein Name: Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1
• Protein Family: Arf-GAP with GTPase, ANK repeat and PH domain-containing protein
• UniProt Gene Name: AGAP1
• UniProt Synonym Gene Names: CENTG2; KIAA1099; AGAP-1; Cnt-g2; GGAP1
• UniProt Entry Name: AGAP1_HUMAN

NCBI Description

This gene encodes a member of an ADP-ribosylation factor GTPase-activating protein family involved in membrane trafficking and cytoskeleton dynamics. This gene functions as a direct regulator of the adaptor-related protein complex 3 on endosomes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Uniprot Description

CENTG2: GTPase-activating protein for ARF1 and, to a lesser extent, ARF5. Directly and specifically regulates the adapter protein 3 (AP-3)-dependent trafficking of proteins in the endosomal-lysosomal system. Belongs to the centaurin gamma-like family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: GAPs, ARF; GAPs

Chromosomal Location of Human Ortholog: 2q37

Cellular Component: cytoplasm

Molecular Function: GTP binding; zinc ion binding; phospholipid binding

Biological Process: protein transport; small GTPase mediated signal transduction; positive regulation of GTPase activity