SDS-Page
(Detection of AFAP. Lysate from human MCF-7 cells was resolved by SDS-PAGE, transferred to an Immobilon-P membrane, and immunoblotted with 1.0ug/ml anti-AFAP, as described in Protocols for Immunoblotting.)
Goat anti-Human AFAP Polyclonal Antibody | anti-AFAP1 antibody
AFAP (actin filament associated protein 1, actin filament associated protein, AFAP, AFAP-110, FLJ56849)
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
SDS-Page
(Detection of AFAP. Lysate from human MCF-7 cells was resolved by SDS-PAGE, transferred to an Immobilon-P membrane, and immunoblotted with 1.0ug/ml anti-AFAP, as described in Protocols for Immunoblotting.)
SDS-Page
(Detection of AFAP. Lysate from human MCF-7 cells was resolved by SDS-PAGE, transferred to an Immobilon-P membrane, and immunoblotted with 1.0ug/ml anti-AFAP, as described in Protocols for Immunoblotting.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a Src binding partner. It may represent a potential modulator of actin filament integrity in response to cellular signals, and may function as an adaptor protein by linking Src family members and/or other signaling proteins to actin filaments. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Uniprot Description
AFAP: Can cross-link actin filaments into both network and bundle structures. May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 4p16
Cellular Component: focal adhesion; cytoplasm; actin cytoskeleton
Molecular Function: actin binding
Biological Process: regulation of signal transduction; regulation of cytoskeleton organization and biogenesis
Research Articles on AFAP1
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Product Notes
The AFAP1 afap1 (Catalog #AAA622056) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The AFAP (actin filament associated protein 1, actin filament associated protein, AFAP, AFAP-110, FLJ56849) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's AFAP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the AFAP1 afap1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AFAP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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