Goat Adrb3 Polyclonal Antibody | anti-Adrb3 antibody
Goat anti-Adrb3 (mouse, intracellular) Antibody
Western Blot: Preliminary experiments gave an approx 48kDa band in Mouse fetal Brain lysates after 0.1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 43. 0kDa according to NP_038490.2. The 48kDa band was successfully blocked by incubation with the immunizing peptide.
NCBI and Uniprot Product Information
Uniprot Description
ADRB3: Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis. Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB3 sub-subfamily.
Protein type: Membrane protein, integral; Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass
Cellular Component: integral to membrane; integral to plasma membrane; membrane; nucleus; plasma membrane; receptor complex
Molecular Function: adrenoceptor activity; beta-3 adrenergic receptor binding; beta-adrenergic receptor activity; beta3-adrenergic receptor activity; epinephrine binding; G-protein coupled receptor activity; norepinephrine binding; protein homodimerization activity; signal transducer activity
Biological Process: adenylate cyclase activation; brown fat cell differentiation; cell-cell signaling; diet induced thermogenesis; eating behavior; G-protein coupled receptor protein signaling pathway; G-protein signaling, adenylate cyclase activating pathway; heat generation; negative regulation of multicellular organism growth; norepinephrine-epinephrine vasodilation involved in regulation of systemic arterial blood pressure; positive regulation of MAPKKK cascade; response to cold; signal transduction
Research Articles on Adrb3
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Product Notes
The Adrb3 adrb3 (Catalog #AAA422834) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-Adrb3 (mouse, intracellular) Antibody reacts with Expected from sequence similarity: Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Adrb3 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA). Peptide ELISA: Antibody detection limit dilution 1: 32000. Western Blot: Preliminary experiments gave an approx 48kDa band in Mouse fetal Brain lysates after 0.1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 43. 0kDa according to NP_038490.2. The 48kDa band was successfully blocked by incubation with the immunizing peptide. Researchers should empirically determine the suitability of the Adrb3 adrb3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: EARQSPPLNR FD. It is sometimes possible for the material contained within the vial of "Adrb3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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