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Guinea Pig Adipophilin Polyclonal Antibody | anti-PLIN2 antibody

Adipophilin (C terminal) antibody

Gene Names
PLIN2; ADFP; ADRP
Reactivity
Human Adipophilin C-terminal
Applications
Immunohistochemistry, Western Blot
Synonyms
Adipophilin; Polyclonal Antibody; Adipophilin (C terminal) antibody; Polyclonal Adipophilin; Anti Adipophilin; anti-PLIN2 antibody
Ordering
For Research Use Only!
Host
Guinea Pig
Reactivity
Human Adipophilin C-terminal
Clonality
Polyclonal
Specificity
Human Adipophilin C-terminal
Form/Format
Supplied in liquid form. Contains 0.09% sodium azide
Sequence Length
437
Applicable Applications for anti-PLIN2 antibody
Immunohistochemistry (IHC), Western Blot (WB)
Application Notes
IHC: 1:100
WB: 1:2000
Biological Significance
Adipophilin/ADRP (a member of the PAT family) is a ubiquitous component of lipid droplets. It has been found in milk fat globule membranes and on the surface of lipid droplets in various cultured cell lines inducible by etomoxir. Enhanced expression of Adipophilin/ADRP is a useful marker for pathologies characterized by increased lipid droplet accumulation. Such diseases include atheroma, steatosis, obesity and certain cases of liposarcoma. It also seems to be a potent marker for atherosclerosis.
Immunogen
Adipophilin (C terminal) antibody was raised in Guinea Pig using synthetic peptide C-terminal aa 423 - 437 of human adipophilin as the immunogen.
Preparation and Storage
Store at 2-8 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-PLIN2 antibody
Guinea Pig polyclonal Adipophilin C terminal antibody
Product Categories/Family for anti-PLIN2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
123
UniProt Accession #
Molecular Weight
48,075 Da
NCBI Official Full Name
adipophilin, partial
NCBI Official Synonym Full Names
perilipin 2
NCBI Official Symbol
PLIN2
NCBI Official Synonym Symbols
ADFP; ADRP
NCBI Protein Information
perilipin-2
UniProt Protein Name
Perilipin-2
Protein Family
UniProt Gene Name
PLIN2
UniProt Synonym Gene Names
ADFP; ADRP
UniProt Entry Name
PLIN2_HUMAN

NCBI Description

The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011]

Uniprot Description

perilipin 2: May be involved in development and maintenance of adipose tissue. Belongs to the perilipin family.

Protein type: Endoplasmic reticulum

Chromosomal Location of Human Ortholog: 9p22.1

Cellular Component: endoplasmic reticulum; extracellular region; plasma membrane; lipid particle; cytosol; nucleus

Biological Process: response to drug; long-chain fatty acid transport; sequestering of lipid; cellular lipid metabolic process; response to organic cyclic substance

Research Articles on PLIN2

Similar Products

Product Notes

The PLIN2 plin2 (Catalog #AAA835127) is an Antibody produced from Guinea Pig and is intended for research purposes only. The product is available for immediate purchase. The Adipophilin (C terminal) antibody reacts with Human Adipophilin C-terminal and may cross-react with other species as described in the data sheet. AAA Biotech's Adipophilin can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). IHC: 1:100 WB: 1:2000. Researchers should empirically determine the suitability of the PLIN2 plin2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Adipophilin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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