Western Blot (WB)
(Western Blot analysis of extracts of various cell lines, using ADI1 antibody at 1:3000 dilution.)
Rabbit anti-Human ADI1 Polyclonal Antibody | anti-ADI1 antibody
ADI1 Polyclonal Antibody
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot analysis of extracts of various cell lines, using ADI1 antibody at 1:3000 dilution.)
Western Blot (WB)
(Western Blot analysis of extracts of various cell lines, using ADI1 antibody at 1:3000 dilution.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an enzyme that belongs to the aci-reductone dioxygenase family of metal-binding enzymes, which are involved in methionine salvage. This enzyme may regulate mRNA processing in the nucleus, and may carry out different functions depending on its localization. Related pseudogenes have been defined on chromosomes 8 and 20. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
Uniprot Description
ADI1: Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Necessary for hepatitis C virus replication in an otherwise non-permissive cell line. Belongs to the acireductone dioxygenase (ARD) family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Amino Acid Metabolism - cysteine and methionine; EC 1.13.11.54; Oxidoreductase
Chromosomal Location of Human Ortholog: 2p25.3
Cellular Component: nucleoplasm; Golgi apparatus; cytoplasm; plasma membrane; nucleus; cytosol
Molecular Function: acireductone dioxygenase [iron(II)-requiring] activity; protein binding; iron ion binding; oxidoreductase activity
Biological Process: methionine salvage; sulfur amino acid metabolic process; polyamine metabolic process
Research Articles on ADI1
Similar Products
Product Notes
The ADI1 adi1 (Catalog #AAA3009917) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ADI1 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ADI1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the ADI1 adi1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ADI1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
