Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Rabbit anti-Mouse Adenylate Cyclase Activating Polypeptide 1, Pituitary (ADCYAP1) Polyclonal Antibody | anti-ADCYAP1 antibody
Polyclonal Antibody to Adenylate Cyclase Activating Polypeptide 1, Pituitary (ADCYAP1)
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- MTMCSGARLA LLVYGIIMHS SVSCSPAAGL SFPGIRPEDE AYDQDGNPLQ DFYDWDPPGV GSPASALRDA YALYYPADRR DVAHEILNEA YRKVLDQLSA RKYLQSVVAR GAGENLGGSA VDDPAPLTKR HSDGIFTDSY
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Brain Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Brain Tissue))
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded Brain tissue))
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded Brain tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Testis Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Testis Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Testis Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Testis Tissue))
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the glucagon superfamily of hormones that have important roles in growth and metabolism. The encoded protein undergoes proteolytic processing to generate mature peptides that function as hypophysiotropic hormones, neurotransmitters, neuromodulators and vasoregulators. Mice lacking the encoded protein exhibit a high rate of early mortality. The surviving adult animals lacking the encoded protein exhibit decreased anxiety, hyperactive behavior and impaired steroidogenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2015]
Uniprot Description
ADCYAP1: Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Belongs to the glucagon family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 17|17 E5
Cellular Component: extracellular region; extracellular space; terminal bouton
Molecular Function: hormone activity; neuropeptide hormone activity; peptide hormone receptor binding; pituitary adenylate cyclase activating polypeptide activity; pituitary adenylate cyclase-activating polypeptide receptor binding; receptor binding; receptor signaling protein activity
Biological Process: adenylate cyclase activation; ATP metabolic process; behavioral fear response; cAMP-mediated signaling; elevation of cytosolic calcium ion concentration; histamine secretion; insulin secretion; negative regulation of acute inflammatory response to antigenic stimulus; negative regulation of acute inflammatory response to non-antigenic stimulus; negative regulation of cell cycle; negative regulation of potassium ion transport; nervous system development; neuron projection development; neuropeptide signaling pathway; ovarian follicle development; positive regulation of adenylate cyclase activity; positive regulation of cAMP biosynthetic process; positive regulation of cell proliferation; positive regulation of growth hormone secretion; positive regulation of GTPase activity; positive regulation of interleukin-6 production; positive regulation of protein kinase activity; positive regulation of synaptic transmission, glutamatergic; positive regulation of transcription from RNA polymerase II promoter; regulation of G-protein coupled receptor protein signaling pathway; regulation of postsynaptic membrane potential; regulation of protein amino acid phosphorylation; regulation of protein localization; sensory perception of pain
Research Articles on ADCYAP1
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Product Notes
The ADCYAP1 adcyap1 (Catalog #AAA2015022) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Adenylate Cyclase Activating Polypeptide 1, Pituitary (ADCYAP1) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Adenylate Cyclase Activating Polypeptide 1, Pituitary (ADCYAP1) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the ADCYAP1 adcyap1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- MTMCSGARLA LLVYGIIMHS SVSCSPAAGL SFPGIRPEDE AYDQDGNPLQ DFYDWDPPGV GSPASALRDA YALYYPADRR DVAHEILNEA YRKVLDQLSA RKYLQSVVAR GAGENLGGSA VDDPAPLTKR HSDGIFTDSY. It is sometimes possible for the material contained within the vial of "Adenylate Cyclase Activating Polypeptide 1, Pituitary (ADCYAP1), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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