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Typical Testing Data/Standard Curve (for reference only)

Mouse Pituitary adenylate cyclase-activating polypeptide ELISA Kit | Adcyap1 elisa kit

Mouse Pituitary adenylate cyclase-activating polypeptide ELISA Kit

Gene Names
Adcyap1; PACAP
Reactivity
Mouse
Synonyms
Pituitary adenylate cyclase-activating polypeptide; Mouse Pituitary adenylate cyclase-activating polypeptide ELISA Kit; PACAP; Adcyap1; Pacap; Adcyap1 elisa kit
Ordering
For Research Use Only!
Reactivity
Mouse
Sequence Length
175
Assay Type
Sandwich
Detection Range
6.25-400 pg/mL
Sensitivity
3.125 pg/mL
Intra-Assay CV
<=6.8%
Inter-Assay CV
<=8.7%
Recovery
108%
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
19,381 Da
NCBI Official Full Name
pituitary adenylate cyclase-activating polypeptide isoform 1 preproprotein
NCBI Official Synonym Full Names
adenylate cyclase activating polypeptide 1
NCBI Official Symbol
Adcyap1
NCBI Official Synonym Symbols
PACAP
NCBI Protein Information
pituitary adenylate cyclase-activating polypeptide
UniProt Protein Name
Pituitary adenylate cyclase-activating polypeptide
UniProt Gene Name
Adcyap1
UniProt Synonym Gene Names
Pacap; PACAP; PACAP-27; PACAP27; PACAP-38; PACAP38
UniProt Entry Name
PACA_MOUSE

NCBI Description

This gene encodes a member of the glucagon superfamily of hormones that have important roles in growth and metabolism. The encoded protein undergoes proteolytic processing to generate mature peptides that function as hypophysiotropic hormones, neurotransmitters, neuromodulators and vasoregulators. Mice lacking the encoded protein exhibit a high rate of early mortality. The surviving adult animals lacking the encoded protein exhibit decreased anxiety, hyperactive behavior and impaired steroidogenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2015]

Uniprot Description

ADCYAP1: Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Belongs to the glucagon family.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: extracellular region; extracellular space; intracellular; terminal button

Molecular Function: hormone activity; neuropeptide hormone activity; peptide hormone receptor binding; pituitary adenylate cyclase activating polypeptide activity; pituitary adenylate cyclase-activating peptide receptor binding; receptor binding; receptor signaling protein activity

Biological Process: adenylate cyclase activation; ATP metabolic process; behavioral fear response; cAMP-mediated signaling; elevation of cytosolic calcium ion concentration; histamine secretion; negative regulation of acute inflammatory response to antigenic stimulus; negative regulation of acute inflammatory response to non-antigenic stimulus; negative regulation of cell cycle; negative regulation of potassium ion transport; nervous system development; neurite development; neuropeptide signaling pathway; ovarian follicle development; positive regulation of cAMP biosynthetic process; positive regulation of cell proliferation; positive regulation of growth hormone secretion; positive regulation of GTPase activity; positive regulation of interleukin-6 production; positive regulation of protein kinase activity; positive regulation of synaptic transmission, glutamatergic; positive regulation of transcription from RNA polymerase II promoter; positive regulation of vasodilation; regulation of G-protein coupled receptor protein signaling pathway; regulation of postsynaptic membrane potential; regulation of protein localization; sensory perception of pain

Research Articles on Adcyap1

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Product Notes

The Mouse Adcyap1 adcyap1 (Catalog #AAA289963) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA289963 ELISA Kit recognizes Mouse Adcyap1. It is sometimes possible for the material contained within the vial of "Pituitary adenylate cyclase-activating polypeptide, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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