Rabbit ADCY3 Polyclonal Antibody | anti-ADCY3 antibody

ADCY3 Rabbit Polyclonal

Cat. Num. AAA766388

• Gene Names: ADCY3; AC3; AC-III
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: ADCY3; Polyclonal Antibody; ADCY3 Rabbit Polyclonal; anti-ADCY3 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 1145

• Applicable Applications for anti-ADCY3 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Immunogen: Adenylate cyclase 3
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human kidney using MBS766388 (ADCY3 antibody) at dilution of 1:100)

Western Blot (WB)

(mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with MBS766388 (ADCY3 antibody) at dilution of 1:300)

NCBI and Uniprot Product Information

• NCBI GI #: 1002341785
• NCBI GeneID: 109
• NCBI Accession #: NP_001307542.1
• NCBI GenBank Nucleotide #: NM_001320613.1
• Molecular Weight: 82,289 Da
• NCBI Official Full Name: adenylate cyclase type 3 isoform 1
• NCBI Official Synonym Full Names: adenylate cyclase 3
• NCBI Official Symbol: ADCY3
• NCBI Official Synonym Symbols: AC3; AC-III
• NCBI Protein Information: adenylate cyclase type 3
• UniProt Protein Name: Adenylate cyclase type 3
• Protein Family: Adenylate cyclase
• UniProt Gene Name: ADCY3
• UniProt Synonym Gene Names: KIAA0511; AC-III; AC3
• UniProt Entry Name: ADCY3_HUMAN

NCBI Description

This gene encodes adenylyl cyclase 3 which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This protein appears to be widely expressed in various human tissues and may be involved in a number of physiological and pathophysiological metabolic processes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]

Uniprot Description

ADCY3: a membrane-associated enzyme that catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Widely expressed in various human tissues and may be involved in a number of physiological and pathophysiological metabolic processes. Involved in odorant detection (possibly) via modulation of intracellular cAMP concentration.

Protein type: Membrane protein, integral; Transporter, aquaporin family; Transporter; Adenylyl cyclase; EC 4.6.1.1; Nucleotide Metabolism - purine; Membrane protein, multi-pass; Lyase

Chromosomal Location of Human Ortholog: 2p23.3

Cellular Component: cilium; cytoplasm; Golgi apparatus; integral to membrane; integral to plasma membrane; lipid raft; membrane; nucleus; plasma membrane

Molecular Function: adenylate cyclase activity; ATP binding; calcium- and calmodulin-responsive adenylate cyclase activity; calmodulin binding; metal ion binding

Biological Process: acrosome reaction; activation of protein kinase A; adenylate cyclase activation; cAMP biosynthetic process; cAMP-mediated signaling; female meiosis; G-protein signaling, adenylate cyclase activating pathway; G-protein signaling, adenylate cyclase inhibiting pathway; olfactory learning; renal water homeostasis; sensory perception of smell; signal transduction; single fertilization; sperm motility