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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded section of Rat Cardiac Muscle Tissue)

Rabbit ADAMTS2 Polyclonal Antibody | anti-ADAMTS2 antibody

ADAMTS2 Antibody

Gene Names
ADAMTS2; NPI; PNPI; PCINP; PCPNI; PCI-NP; PC I-NP; ADAM-TS2; ADAMTS-2; ADAMTS-3; EDSDERMS
Applications
Western Blot, Immunohistochemistry
Purity
Affinity Chromatography
Synonyms
ADAMTS2; Polyclonal Antibody; ADAMTS2 Antibody; Affinity Purified Rabbit Polyclonal ADAMTS2 Antibody; Polyclonal ADAMTS2 antibody; Anti-ADAMTS2 antibody; ADAMTS-2 antibody; ADAMTS 2 antibody; ADAMTS-2; Procollagen I N-proteinase antibody; ADAMTS 2; PC I-NP antibody; anti-ADAMTS2 antibody
Ordering
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Chromatography
Form/Format
Lyophilized Form
Sequence Length
1211
Applicable Applications for anti-ADAMTS2 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin
Immunogen
ADAMTS2 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human ADAMTS2, different from the related rat and Rabbit sequences by three amino acids, as the immunogen
Preparation and Storage
Store at 4 degree C for short term storage. For long term storage aliquot and store at -20 degree C. Avoid repeated freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded section of Rat Cardiac Muscle Tissue)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded section of Rat Cardiac Muscle Tissue)

Western Blot (WB)

(Lane 1: Rat Brain Tissue Lysate; Lane 2: Rat Heart Tissue Lysate)

Western Blot (WB) (Lane 1: Rat Brain Tissue Lysate; Lane 2: Rat Heart Tissue Lysate)
Related Product Information for anti-ADAMTS2 antibody
ADAMTS2, A disintegrin and metalloproteinase with thrombospondin motifs 2, also known as procollagen I N-proteinase (PC I-NP), is an enzyme that in humans is encoded by the ADAMTS2 gene. The ADAMTS2 gene contains 22 exons. The human ADAMTS2 gene is mapped to chromosome 5q23-q24 by analysis of somatic cell hybrids. ADAMTS2 is responsible for processing several types of procollagen proteins. Procollagens are the precursors of collagens, the proteins that add strength and support to many body tissues. Specifically, this enzyme clips a short chain of amino acids off one end of the procollagen. This clipping step is necessary for collagen molecules to function normally and assemble into fibrils outside cells.
Product Categories/Family for anti-ADAMTS2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
A disintegrin and metalloproteinase with thrombospondin motifs 2 isoform 1 preproprotein
NCBI Official Synonym Full Names
ADAM metallopeptidase with thrombospondin type 1 motif 2
NCBI Official Symbol
ADAMTS2
NCBI Official Synonym Symbols
NPI; PNPI; PCINP; PCPNI; PCI-NP; PC I-NP; ADAM-TS2; ADAMTS-2; ADAMTS-3; EDSDERMS
NCBI Protein Information
A disintegrin and metalloproteinase with thrombospondin motifs 2
UniProt Protein Name
A disintegrin and metalloproteinase with thrombospondin motifs 2
UniProt Gene Name
ADAMTS2
UniProt Synonym Gene Names
PCINP; PCPNI; ADAM-TS 2; ADAM-TS2; ADAMTS-2; PC I-NP; pNPI

NCBI Description

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature procollagen N-proteinase. This proteinase excises the N-propeptide of the fibrillar procollagens types I-III and type V. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]

Uniprot Description

Cleaves the propeptides of type I and II collagen prior to fibril assembly. Does not act on type III collagen. May also play a role in development that is independent of its role in collagen biosynthesis.CautionHas sometimes been referred to as ADAMTS3.

Research Articles on ADAMTS2

Similar Products

Product Notes

The ADAMTS2 adamts2 (Catalog #AAA5312775) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's ADAMTS2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin. Researchers should empirically determine the suitability of the ADAMTS2 adamts2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ADAMTS2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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