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Western Blot (WB) (Western blot analysis of 50 ug of whole cell lysate (A: Mouse brain) using a 10% SDS PAGE gel and ACMSD antibody at a dilution of 1:1000)

Rabbit ACMSD Polyclonal Antibody | anti-ACMSD antibody

ACMSD Antibody

Applications
Immunohistochemistry, Western Blot
Purity
Antigen-Affinity Chromatography
Synonyms
ACMSD; Polyclonal Antibody; ACMSD Antibody; Affinity Purified Rabbit Polyclonal ACMSD Antibody; Polyclonal ACMSD antibody; Anti-ACMSD antibody; 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase antibody; aminocarboxymuconate semialdehyde decarboxylase antibody; ACMSD antibody; picolinate carboxylase antibody; anti-ACMSD antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen-Affinity Chromatography
Form/Format
Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration
1 mg/ml (varies by lot)
Sequence Length
278
Applicable Applications for anti-ACMSD antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
IHC-P: 1:100-1:500
WB: 1:500-1:3000
Immunogen
ACMSD antibody was raised in rabbit using a recombinant protein fragment contain a sequence corresponding to a region within amino acids 105 and 297 of ACMSD
Cross-Reactivity
Human, Mouse
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of 50 ug of whole cell lysate (A: Mouse brain) using a 10% SDS PAGE gel and ACMSD antibody at a dilution of 1:1000)

Western Blot (WB) (Western blot analysis of 50 ug of whole cell lysate (A: Mouse brain) using a 10% SDS PAGE gel and ACMSD antibody at a dilution of 1:1000)

Western Blot (WB)

(Western blot analysis of 30 ug of whole cell lysate (A: Molt-4; B: Raji) using a 10% SDS PAGE gel and ACMSD antibody at a dilution of 1:1000)

Western Blot (WB) (Western blot analysis of 30 ug of whole cell lysate (A: Molt-4; B: Raji) using a 10% SDS PAGE gel and ACMSD antibody at a dilution of 1:1000)

Immunohistochemistry (IHC)

(Immunohistochemical staining of paraffin-embedded SAS xenograft using ACMSD antibody at a dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemical staining of paraffin-embedded SAS xenograft using ACMSD antibody at a dilution of 1:100)
Related Product Information for anti-ACMSD antibody
The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde. ACMSD can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.
Product Categories/Family for anti-ACMSD antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
38 kDa
NCBI Official Full Name
ACMSD protein
NCBI Official Synonym Full Names
aminocarboxymuconate semialdehyde decarboxylase
NCBI Official Symbol
ACMSD
NCBI Protein Information
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase

NCBI Description

The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.[supplied by OMIM, Oct 2004]

Research Articles on ACMSD

Similar Products

Product Notes

The ACMSD (Catalog #AAA5312109) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's ACMSD can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P: 1:100-1:500 WB: 1:500-1:3000. Researchers should empirically determine the suitability of the ACMSD for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ACMSD, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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