Testing Data
(MBS616181 staining of rat dorsal root ganglia using anti-rabbit Cy3 (red color) secondary antibodies.)
Rabbit anti-Human, Rat Acid Sensitive Ion Channel 2b Polyclonal Antibody
Acid Sensitive Ion Channel 2b (ASIC2B, MDEG2 Mammalian Degenerin2)
Reactivity
Human, Rat
Applications
Immunohistochemistry
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
Acid Sensitive Ion Channel 2b; Polyclonal Antibody; Acid Sensitive Ion Channel 2b (ASIC2B; MDEG2 Mammalian Degenerin2); Anti -Acid Sensitive Ion Channel 2b (ASIC2B; anti-Acid Sensitive Ion Channel 2b antibody
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human Acid Sensitive Ion Channel 2b. Species Crossreactivity: rat.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, 0.05% sodium azide.
Applicable Applications for anti-Acid Sensitive Ion Channel 2b antibody
Immunohistochemistry (IHC)
Application Notes
Suitable for use in Immunohistochemistry.
Dilution: Immunohistochemistry: 1:300-1:3000
Dilution: Immunohistochemistry: 1:300-1:3000
Immunogen
Synthetic peptide corresponding to aa15-26, CSGPGRFMAREQ of human ASIC 2B.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Testing Data
(MBS616181 staining of rat dorsal root ganglia using anti-rabbit Cy3 (red color) secondary antibodies.)
Testing Data
(MBS616181 staining of rat dorsal root ganglia using anti-rabbit Cy3 (red color) secondary antibodies.)
Related Product Information for anti-Acid Sensitive Ion Channel 2b antibody
Tissue acidosis that occurs in ischemia, tissue damage or inflammation is accompanied by pain. Proton-gated cation channels are activated by low pH in nociceptive neurons. H+-gated channels are members of the NaC/DEG superfamily that include: (1) Amiloride-sensitive epithelial Na+ channels (a, b, g, and d-ENaC subunits); (2) A FMRFamide-gated channel (FaNaC); (3) mechanosensory channel proteins of nematode degenerins (DEG). NaC/DEG superfamily is characterized by intracellular N and C-termini, two transmembrane domains, and a large extracellular loop. All members of this family are selective for Na+ and blocked by amiloride.
Product Categories/Family for anti-Acid Sensitive Ion Channel 2b antibody
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Product Notes
The Acid Sensitive Ion Channel 2b (Catalog #AAA616181) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Acid Sensitive Ion Channel 2b (ASIC2B, MDEG2 Mammalian Degenerin2) reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Acid Sensitive Ion Channel 2b can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Suitable for use in Immunohistochemistry. Dilution: Immunohistochemistry: 1:300-1:3000. Researchers should empirically determine the suitability of the Acid Sensitive Ion Channel 2b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Acid Sensitive Ion Channel 2b, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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